使用布朗斯特酸性离子液体作为高效催化剂，将吲哚共轭加成到α,β-不饱和酮上。
Conjugate addition of indoles to alpha,beta-unsaturated ketones using a Brønsted acid ionic liquid as an efficient catalyst.
作者信息
Yu Chuan-Ji, Liu Chen-Jiang
机构信息
School of Chemistry and Chemical Engineering, Xinjiang University, Key Laboratory of Oil and Gas Fine Chemicals, Ministry of Education, 830046 Urumqi, China.
出版信息
Molecules. 2009 Aug 27;14(9):3222-8. doi: 10.3390/molecules14093222.
The Brønsted acid ionic liquid [PyN(CH(2))(4)SO(3)H][p-CH(3)PhSO(3)] has been reported as an efficient catalyst for the Michael addition reaction of indoles to alpha,beta-unsaturated ketones. Satisfactory results were obtained, with excellent yields and a simple experimental procedure. The catalyst could be recycled and reused up to three times without any noticeable decrease in the catalytic activity.
布朗斯特酸性离子液体[PyN(CH(2))(4)SO(3)H][p-CH(3)PhSO(3)]已被报道为吲哚与α,β-不饱和酮的迈克尔加成反应的有效催化剂。该反应获得了令人满意的结果，产率优异且实验步骤简单。该催化剂可以循环使用多达三次，而催化活性没有任何明显下降。
Zotero 插件