• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

木犀草素-磷脂复合物的理化性质及抗氧化活性

Physicochemical properties and antioxidant activities of luteolin-phospholipid complex.

作者信息

Xu Keyong, Liu Benguo, Ma Yuxiang, Du Jiquan, Li Guanglei, Gao Han, Zhang Yuan, Ning Zhengxiang

机构信息

College of Light Industry and Food Science, South China University of Technology, Guangzhou 510640, China.

出版信息

Molecules. 2009 Sep 9;14(9):3486-93. doi: 10.3390/molecules14093486.

DOI:10.3390/molecules14093486
PMID:19783938
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6254978/
Abstract

A luteolin and phospholipid complex was prepared to improve the lipophilic properties of luteolin. The physicochemical properties of the complex were analyzed by ultraviolet-visible spectrometry (UV), infrared spectrometry (IR), X-ray diffractometry (XRD) and differential scanning calorimetry (DSC). The results showed that luteolin and phospholipid in the complex were joined by non-covalent-bonds and did not form a new compound. It was found that the complex was an effective scavenger of DPPH radicals, with an IC(50) value of 28.33 microg/mL. In the Rancimat antioxidant test using lard oil as substrate, the complex also showed the strong antioxidant activity.

摘要

制备了木犀草素与磷脂的复合物以改善木犀草素的亲脂性。通过紫外可见光谱法（UV）、红外光谱法（IR）、X射线衍射法（XRD）和差示扫描量热法（DSC）分析了该复合物的理化性质。结果表明，复合物中的木犀草素与磷脂通过非共价键结合，未形成新的化合物。发现该复合物是DPPH自由基的有效清除剂，IC(50)值为28.33微克/毫升。在以猪油为底物的Rancimat抗氧化试验中，该复合物也表现出较强的抗氧化活性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7157/6254978/0976ac5e7f6a/molecules-14-03486-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7157/6254978/c3afab8a9377/molecules-14-03486-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7157/6254978/68e30665aded/molecules-14-03486-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7157/6254978/15a3c4bec87d/molecules-14-03486-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7157/6254978/130544904813/molecules-14-03486-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7157/6254978/96be1982c23b/molecules-14-03486-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7157/6254978/d553188cf597/molecules-14-03486-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7157/6254978/0976ac5e7f6a/molecules-14-03486-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7157/6254978/c3afab8a9377/molecules-14-03486-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7157/6254978/68e30665aded/molecules-14-03486-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7157/6254978/15a3c4bec87d/molecules-14-03486-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7157/6254978/130544904813/molecules-14-03486-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7157/6254978/96be1982c23b/molecules-14-03486-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7157/6254978/d553188cf597/molecules-14-03486-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7157/6254978/0976ac5e7f6a/molecules-14-03486-g007.jpg

相似文献

1
Physicochemical properties and antioxidant activities of luteolin-phospholipid complex.木犀草素-磷脂复合物的理化性质及抗氧化活性
Molecules. 2009 Sep 9;14(9):3486-93. doi: 10.3390/molecules14093486.
2
Synthesis, Spectroscopic Study and Radical Scavenging Activity of Kaempferol Derivatives: Enhanced Water Solubility and Antioxidant Activity.金雀异黄素衍生物的合成、光谱研究及自由基清除活性：提高水溶性和抗氧化活性。
Int J Mol Sci. 2019 Feb 23;20(4):975. doi: 10.3390/ijms20040975.
3
Preparation and physicochemical properties of the complex of naringenin with hydroxypropyl-beta-cyclodextrin.柚皮素与羟丙基-β-环糊精包合物的制备及理化性质。
Molecules. 2010 Jun 18;15(6):4401-7. doi: 10.3390/molecules15064401.
4
Direct electrospinning for producing multiple activity nanofibers consisting of aggregated luteolin/hydroxypropyl-gamma-cyclodextrin inclusion complex.用于制备由聚集的木犀草素/羟丙基-γ-环糊精包合物组成的具有多种活性的纳米纤维的直接静电纺丝法。
Int J Biol Macromol. 2024 Jun;270(Pt 1):132344. doi: 10.1016/j.ijbiomac.2024.132344. Epub 2024 May 14.
5
Physicochemical characterisation of the supramolecular structure of luteolin/cyclodextrin inclusion complex.芦丁/环糊精包合物超分子结构的物理化学特性。
Food Chem. 2013 Nov 15;141(2):900-6. doi: 10.1016/j.foodchem.2013.03.097. Epub 2013 Apr 13.
6
Radical Scavenging Properties of Roasted Egoma (Perilla frutescens var. frutescens) Oils and Identification of Their Characteristic Scavengers.烤荏胡麻（紫苏变种）油的自由基清除特性及其特征清除剂的鉴定
J Nutr Sci Vitaminol (Tokyo). 2018;64(6):466-472. doi: 10.3177/jnsv.64.466.
7
Antioxidative components from the aerial parts of Lactuca scariola L.苣荬菜地上部分的抗氧化成分
Arch Pharm Res. 2001 Oct;24(5):427-30. doi: 10.1007/BF02975189.
8
The effects of C-glycosylation of luteolin on its antioxidant, anti-Alzheimer's disease, anti-diabetic, and anti-inflammatory activities.木樨草素 C-糖苷化对其抗氧化、抗老年痴呆症、抗糖尿病和抗炎活性的影响。
Arch Pharm Res. 2014 Oct;37(10):1354-63. doi: 10.1007/s12272-014-0351-3. Epub 2014 Mar 24.
9
Nickel oxide nanoparticles: a novel antioxidant.氧化镍纳米颗粒：一种新型抗氧化剂。
Colloids Surf B Biointerfaces. 2010 Jun 15;78(1):146-8. doi: 10.1016/j.colsurfb.2010.02.016. Epub 2010 Feb 19.
10
Synthesis, characterisation and antioxidant activity of luteolin-vanadium(II) complex.木犀草素 - 钒（II）配合物的合成、表征及抗氧化活性
Food Chem. 2015 Apr 15;173:1172-8. doi: 10.1016/j.foodchem.2014.10.141. Epub 2014 Nov 3.

引用本文的文献

1
Luteolin: a natural product with multiple mechanisms for atherosclerosis.木犀草素：一种具有多种抗动脉粥样硬化机制的天然产物。
Front Pharmacol. 2025 Mar 27;16:1503832. doi: 10.3389/fphar.2025.1503832. eCollection 2025.
2
Ultrasound-assisted preparation of wax-based composite gelator: Structural characterisation, in vitro antioxidant activity and application in oleogels.超声辅助制备蜡基复合凝胶剂：结构表征、体外抗氧化活性及在油凝胶中的应用
Ultrason Sonochem. 2025 Mar;114:107253. doi: 10.1016/j.ultsonch.2025.107253. Epub 2025 Feb 9.
3
A theoretical study on the mechanism and rate constants of luteolin and selenium dioxide.

本文引用的文献

1
Luteolin reduces IL-6 production in microglia by inhibiting JNK phosphorylation and activation of AP-1.木犀草素通过抑制JNK磷酸化和AP-1的激活来减少小胶质细胞中IL-6的产生。
Proc Natl Acad Sci U S A. 2008 May 27;105(21):7534-9. doi: 10.1073/pnas.0802865105. Epub 2008 May 19.
2
RP-HPLC analysis of the phenolic compounds of plant extracts. investigation of their antioxidant capacity and antimicrobial activity.植物提取物中酚类化合物的反相高效液相色谱分析。其抗氧化能力和抗菌活性的研究。
J Agric Food Chem. 2005 Feb 23;53(4):1190-5. doi: 10.1021/jf040083t.
3
Study on the bioavailability of baicalin-phospholipid complex by using HPLC.
木犀草素与二氧化硒反应机理及速率常数的理论研究
J Mol Model. 2025 Jan 30;31(2):68. doi: 10.1007/s00894-025-06291-1.
4
Dietary Polyphenols: Review on Chemistry/Sources, Bioavailability/Metabolism, Antioxidant Effects, and Their Role in Disease Management.膳食多酚：化学/来源、生物利用度/代谢、抗氧化作用及其在疾病管理中的作用综述
Antioxidants (Basel). 2024 Mar 30;13(4):429. doi: 10.3390/antiox13040429.
5
Topical application of synthetic melanin promotes tissue repair.合成黑色素的局部应用可促进组织修复。
NPJ Regen Med. 2023 Nov 2;8(1):61. doi: 10.1038/s41536-023-00331-1.
6
Luteolin: A promising natural agent in management of pain in chronic conditions.木犀草素：一种用于治疗慢性疾病疼痛的有前景的天然药物。
Front Pain Res (Lausanne). 2023 Mar 1;4:1114428. doi: 10.3389/fpain.2023.1114428. eCollection 2023.
7
Hepatoprotective Effects of Bioflavonoid Luteolin Using Self-Nanoemulsifying Drug Delivery System.采用自微乳药物传递系统的类黄酮木樨草素的保肝作用。
Molecules. 2021 Dec 11;26(24):7497. doi: 10.3390/molecules26247497.
8
Promoted Antitumor Activity of Myricetin against Lung Carcinoma Via Nanoencapsulated Phospholipid Complex in Respirable Microparticles.纳米磷脂复合物包封可吸入微球中杨梅素对肺癌的促肿瘤活性。
Pharm Res. 2020 Apr 14;37(4):82. doi: 10.1007/s11095-020-02794-z.
9
Phyto-phospholipid complexes (phytosomes): A novel strategy to improve the bioavailability of active constituents.植物磷脂复合物（植物脂质体）：提高活性成分生物利用度的新策略。
Asian J Pharm Sci. 2019 May;14(3):265-274. doi: 10.1016/j.ajps.2018.05.011. Epub 2018 Jul 27.
10
Co-delivery with nano-quercetin enhances doxorubicin-mediated cytotoxicity against MCF-7 cells.与纳米槲皮素共同递送可增强阿霉素对MCF-7细胞的细胞毒性作用。
Mol Biol Rep. 2016 Feb;43(2):99-105. doi: 10.1007/s11033-016-3942-x. Epub 2016 Jan 9.
采用高效液相色谱法研究黄芩苷-磷脂复合物的生物利用度。
Biomed Chromatogr. 1999 Nov;13(7):493-5. doi: 10.1002/(SICI)1099-0801(199911)13:7<493::AID-BMC915>3.0.CO;2-A.
4
Intestinal absorption of luteolin and luteolin 7-O-beta-glucoside in rats and humans.大鼠和人体中木犀草素及木犀草素7 - O - β - 葡萄糖苷的肠道吸收情况。
FEBS Lett. 1998 Nov 6;438(3):220-4. doi: 10.1016/s0014-5793(98)01304-0.