[The production of cyclic nucleotides, cyclases and prostaglandins in patients with chronic enteritis].

A study of adenylatecyclase (AC), guanylatecyclase (GC), cAMP, cGMP in the small intestine mucosa and PGE2 and PGP2 in the blood serum of 34 patients with chronic enteritis showed that development of the malabsorption syndrome, diarrhea, structural changes of the small intestine mucosa is influenced by changes in the PGE-AC-cAMP and PGP-AC-cGMP systems. Thus, average-severe and severe course of the disease was accompanied by an increase in the biopsy material of the small intestine mucosa of AC, GC, cAMP, cGMP and PGP2 in the blood.