Meydani Ahou, Schwartz Robert A, Foye Patrick M, Patel Atul D
New Jersey Medical School, 185 South Orange Avenue, Newark, NJ 07103, USA.
Acta Dermatovenerol Alp Pannonica Adriat. 2009 Sep;18(3):135-7.
Localized herpes simplex (HSV) type II following intra-articular corticosteroid injection is remarkable. We describe a 51-year-old woman with sacroiliitis following a fall. She was treated with an intra-articular injection of 80 mg methylprednisolone into her sacroiliac joint, followed 2 days later by a cluster of herpetiform vesicles adjacent to the injection site. Swab of punctured vesicles demonstrated HSV type II by polymerase chain reaction. One plausible explanation is HSV reactivation secondary to localized immunosuppression from corticosteroid injection.
关节内注射皮质类固醇后出现的局限性单纯疱疹病毒II型（HSV）感染情况值得关注。我们描述了一名51岁女性，她因跌倒后患上了骶髂关节炎。她接受了在骶髂关节内注射80毫克甲泼尼龙的治疗，两天后在注射部位附近出现了一群疱疹样水疱。对刺破水疱的拭子进行聚合酶链反应检测显示为单纯疱疹病毒II型。一个合理的解释是，皮质类固醇注射导致局部免疫抑制，继发单纯疱疹病毒激活。
