Baumhoer D, Pfaltz M, Seydoux J, Jundt G
Institut für Pathologie, Universitätsspital Basel, Schönbeinstr 40, 4031 Basel, Schweiz.
Pathologe. 2009 Nov;30(6):457-60. doi: 10.1007/s00292-009-1208-2.
We present the unusual case of a cytologically diagnosed Warthin tumor (WT) of long standing with sudden enlargement und subsequent resection. Histologically, the diagnosis of WT was confirmed, but the tumor additionally showed diffuse infiltrates of an adenocarcinoma undergoing unrestrained growth. Warthin tumor with malignant transformation was suspected and radiological staging examinations were conducted. PET scans detected a metastasizing carcinoma of the breast, morphologically identical to the WT infiltrates. Care should always be taken when the diagnosis of malignant WT is made to exclude metastatic disease.
我们报告了一例长期细胞学诊断为沃辛瘤(WT)的罕见病例,该肿瘤突然增大并随后进行了切除。组织学检查证实了WT的诊断,但肿瘤还额外显示出弥漫性浸润的腺癌,呈无节制生长。怀疑为伴有恶性转化的沃辛瘤,并进行了放射学分期检查。PET扫描检测到乳腺转移性癌,其形态与WT浸润灶相同。在诊断恶性WT时应始终谨慎,以排除转移性疾病。