Murín J, Yaghy M
I. interná klinika Lekárskej fakulty UK Bratislava, Slovenská republika.
Vnitr Lek. 2009 Sep;55(9):788-91.
The prevalence of type 2 diabetes mellitus is growing. Vascular disease is here the main cause of morbidity and mortality, and accelerated atherosclerosis is responsible for about 80% of mortality and for about 75% of hospitalizations. In diabetics there is 2-4 times greater risk of ischemic heart disease in comparison to non-diabetics, and this risk is even greater in diabetic-females. Authors put greater attention to pathophysiology of diabetic vascular disease (inflammation and adipose tissue, metabolic and other--AGEs, ADMA--abnormalities, their contribution to endothelial dysfunction). The main concern is devoted to the treatment possibilities of diabetic vascular disease.
2型糖尿病的患病率正在上升。血管疾病是这里发病和死亡的主要原因，加速动脉粥样硬化约占死亡率的80%和住院率的75%。与非糖尿病患者相比，糖尿病患者患缺血性心脏病的风险高2至4倍，而糖尿病女性的这种风险更高。作者更加关注糖尿病血管疾病的病理生理学（炎症与脂肪组织、代谢及其他——晚期糖基化终末产物、不对称二甲基精氨酸——异常情况，它们对内皮功能障碍的影响）。主要关注点在于糖尿病血管疾病的治疗可能性。
