van Donselaar Cees A, Carpay J A Hans
Maasstad Ziekenhuis, afd. Neurologie, Rotterdam, The Netherlands.
Ned Tijdschr Geneeskd. 2009;153:B327.
Epilepsy is very common. The prevalence in the Netherlands is 5:1000 inhabitants. The diagnosis is mostly made on clinical grounds and often incorrectly. If there are doubts about the diagnosis, the patient can be referred to a specialised centre for a seizure registration with an EEG and video recording. The disorder generally responds well to treatment with anti-epileptics. Some 60-70% of patients treated with these remain free of seizures. If medicinal treatment fails then a surgical intervention can be considered. For patients with temporal epilepsy in particular, there is quite a high chance that a surgical intervention will resolve the symptoms. Where it proves difficult to satisfactorily adjust the medication of a patient, stimulation of the left vagus nerve can be considered. Paying more attention to the side effects of the medication and the limitations imposed on the patients can reduce the negative influence of epilepsy on the quality of life.
癫痫非常常见。荷兰的患病率为每1000名居民中有5人患病。诊断大多基于临床依据，且常常有误。如果对诊断存在疑问，患者可被转至专业中心进行癫痫发作登记，并进行脑电图和视频记录。该疾病通常对抗癫痫药物治疗反应良好。接受这些药物治疗的患者中约60 - 70%不再发作。如果药物治疗失败，则可考虑手术干预。特别是对于颞叶癫痫患者，手术干预有相当高的几率缓解症状。当证明难以令人满意地调整患者的药物治疗时，可考虑刺激左侧迷走神经。更多关注药物的副作用以及对患者的限制，可减少癫痫对生活质量的负面影响。
