Section of Decision Sciences and Clinical Systems Modeling, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA.
Vaccine. 2009 Nov 23;27(50):7110-5. doi: 10.1016/j.vaccine.2009.09.056. Epub 2009 Sep 26.
While studies have found influenza vaccination to be cost-effective in older adults (65 years or older), they have not looked at how the vaccine's economic value may vary with the timing of vaccine administration. We developed a set of computer simulation models to evaluate the economic impact of vaccinating older adults at different months. Our models delineated the costs and utility losses in delaying vaccination past October and suggest that policy makers and payors may consider structuring incentives (< or =$2.50 per patient) to vaccinate in October. Our results also suggest that vaccination is still cost-effective through the end of February.
虽然研究发现流感疫苗对老年人（65 岁及以上）具有成本效益，但它们没有研究疫苗的经济价值如何随疫苗接种时间的不同而变化。我们开发了一组计算机模拟模型，以评估在不同月份为老年人接种疫苗的经济影响。我们的模型描述了将疫苗接种推迟到 10 月以后所产生的成本和效用损失，并表明政策制定者和支付方可能会考虑制定激励措施（每位患者<或=2.50 美元），以鼓励在 10 月接种疫苗。我们的结果还表明，疫苗接种在 2 月底之前仍然具有成本效益。
