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Efficacy and effectiveness of influenza vaccines in elderly people: a systematic review.流感疫苗在老年人中的有效性和效果:一项系统评价
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JAMA. 2005 Jan 12;293(2):229-32. doi: 10.1001/jama.293.2.229.
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MMWR Morb Mortal Wkly Rep. 2004 Dec 24;53(50):1183-4.
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Characteristics of long-term-care facility residents associated with receipt of influenza and pneumococcal vaccinations.与流感和肺炎球菌疫苗接种相关的长期护理机构居民特征。
Infect Control Hosp Epidemiol. 2004 Nov;25(11):946-54. doi: 10.1086/502325.
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Use of a mobile cart influenza program for vaccination of hospital employees.使用移动推车流感项目为医院员工接种疫苗。
Infect Control Hosp Epidemiol. 2004 Nov;25(11):918-22. doi: 10.1086/502320.
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Shortage of influenza vaccine in 2000-2001: did it change patient beliefs?2000 - 2001年流感疫苗短缺:这是否改变了患者的观念?
Am J Prev Med. 2003 May;24(4):349-53. doi: 10.1016/s0749-3797(03)00018-7.
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Delayed supply of influenza vaccine and adjunct ACIP influenza vaccine recommendations for the 2000-01 influenza season. Advisory Committee on Immunization Practices.2000 - 2001流感季节流感疫苗供应延迟及免疫实践咨询委员会的辅助流感疫苗建议。免疫实践咨询委员会。
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Effects of influenza vaccination of health-care workers on mortality of elderly people in long-term care: a randomised controlled trial.医护人员接种流感疫苗对长期护理机构中老年人死亡率的影响:一项随机对照试验。
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2004 - 2005年流感疫苗短缺对长期护理机构免疫接种实践的影响。

Impact of the 2004-2005 influenza vaccine shortage on immunization practices in long-term care facilities.

作者信息

Mody Lona, Langa Kenneth M, Malani Preeti N

机构信息

Ann Arbor Veterans Affairs Healthcare System, 2215 Fuller Road, Ann Arbor, MI 48105, USA.

出版信息

Infect Control Hosp Epidemiol. 2006 Apr;27(4):383-7. doi: 10.1086/503179. Epub 2006 Mar 9.

DOI:10.1086/503179
PMID:16622817
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3319392/
Abstract

OBJECTIVE

To assess the response of long-term care facilities (LTCFs) to the 2004-2005 influenza vaccine shortage and the impact on resident and healthcare worker (HCW) immunization rates.

METHODS

A 12-item questionnaire was sent to 824 randomly selected LTCFs in December 2004. The following 2 open-ended questions were also asked: "How did you cope with the vaccine shortage?" and "Who helped you get your supply?" Immunization rates reported by LTCF administrators for 2003-2003 and 2003-2004 were compared with those for 2004-2005. Immunization rates were defined as the proportion of all eligible residents and HCWs who received influenza vaccine.

RESULTS

Responses were received from 380 LTCFs (46.3%), which had a total of 38,447 beds. Resident mean influenza immunization rates (+/-SD) decreased from 85%+/-15.3% in 2002-2003 and 85.1%+/-15.3% in 2003-2004 to 81.9%+/-19.4% in the 2004-2005 influenza season (P=.025). The immunization rates among HCWs also decreased from 51% in 2002-2003 and 2003-2004 to 38.4% in 2004-2005 (P<.001). In response to one of the open-ended questions, 96 facilities (25.3%) reported that they obtained vaccine from 2 or more sources. Eight percent commented on specific intensified infection control efforts, and only 2.3% commented on emergency preparedness.

CONCLUSIONS

The influenza vaccine shortage in 2004-2005 impacted immunization practices of LTCFs across the United States, leading to decreases in both resident and HCW vaccination rates. The significant decrease in vaccination rates in LTCFs is of concern and has broad implications for policy makers working on emergency preparedness for a possible pandemic of influenza.

摘要

目的

评估长期护理机构(LTCFs)对2004 - 2005年流感疫苗短缺的应对措施以及对居民和医护人员(HCW)免疫接种率的影响。

方法

2004年12月向824家随机选择的长期护理机构发送了一份包含12个项目的问卷。还询问了以下两个开放式问题:“你们如何应对疫苗短缺?”以及“谁帮助你们获得疫苗供应?”将长期护理机构管理人员报告的2003 - 2003年和2003 - 2004年的免疫接种率与2004 - 2005年的进行比较。免疫接种率定义为所有符合条件的居民和医护人员中接种流感疫苗的比例。

结果

收到了380家长期护理机构(46.3%)的回复,这些机构共有38447张床位。居民的平均流感免疫接种率(±标准差)从2002 - 2003年的85%±15.3%和2003 - 2004年的85.1%±15.3%降至2004 - 2005年流感季节的81.9%±19.4%(P = 0.025)。医护人员的免疫接种率也从2002 - 2003年和2003 - 2004年的51%降至2004 - 2005年的38.4%(P < 0.001)。针对其中一个开放式问题,96家机构(25.3%)报告称他们从两个或更多来源获得疫苗。8%的机构提到了具体加强的感染控制措施,只有2.3%的机构提到了应急准备。

结论

2004 - 2005年的流感疫苗短缺影响了美国各地长期护理机构的免疫接种工作,导致居民和医护人员的接种率均下降。长期护理机构接种率的显著下降令人担忧,对致力于流感大流行应急准备工作的政策制定者具有广泛影响。