Perkins Jonathan A, Chen Eunice Y, Hoffer Fredric A, Manning Scott C
Division of Pediatric Otolaryngology, Seattle Children's Hospital, Seattle, WA 98105-0371, USA.
Otolaryngol Head Neck Surg. 2009 Oct;141(4):516-521. doi: 10.1016/j.otohns.2009.06.751.
To describe a method of airway infantile hemangioma staging using standardized assessment of airway narrowing, and hemangioma location and volume, as determined with endoscopy and CT angiography.
Case series with chart review.
Tertiary pediatric hospital, 2003-2008.
Subjects included airway hemangioma patients evaluated at a tertiary pediatric hospital. Data collected were age at first symptoms, diagnostic evaluation, percent airway compromise, and estimated hemangioma volume. Data were analyzed with descriptive and Fisher exact statistics.
Twelve patients were identified and seven had complete data sets. Mean age at first symptoms was 1.9 months (SD 1.09 months, range 0.5-4 months). Evaluation consisted of nasopharyngoscopy, microlaryngoscopy, CT angiography, and/or MRI. Mean laryngeal airway narrowing was estimated at 63.75 percent (SD 19.0%, range 40%-90%). Total hemangioma volume was less in patients with isolated (focal) endolaryngeal hemangiomas compared with airway hemangiomas associated with extralaryngeal (segmental) hemangiomas. Airway hemangioma stages were stage one (5 of 12; 41.6%), stage two (6 of 12; 50.0%), and stage three (1 of 12; 8.3%).
This method of airway hemangioma staging may be applicable to treatment planning and used to measure treatment outcomes.
描述一种通过对气道狭窄、血管瘤位置和体积进行标准化评估来对气道婴儿血管瘤进行分期的方法,这些评估通过内镜检查和CT血管造影来确定。
病例系列研究并进行图表回顾。
三级儿科医院,2003年至2008年。
研究对象包括在一家三级儿科医院接受评估的气道血管瘤患者。收集的数据包括首次出现症状时的年龄、诊断评估、气道受压百分比以及估计的血管瘤体积。采用描述性统计和Fisher精确检验对数据进行分析。
共确定了12例患者,其中7例有完整数据集。首次出现症状时的平均年龄为1.9个月(标准差1.09个月,范围0.5 - 4个月)。评估包括鼻咽镜检查、显微喉镜检查、CT血管造影和/或磁共振成像。平均喉部气道狭窄估计为63.75%(标准差19.0%,范围40% - 90%)。与伴有喉外(节段性)血管瘤的气道血管瘤相比,孤立(局灶性)喉内血管瘤患者的总血管瘤体积较小。气道血管瘤分期为一期(12例中的5例;41.6%)、二期(12例中的6例;50.0%)和三期(12例中的1例;8.3%)。
这种气道血管瘤分期方法可能适用于治疗方案的制定,并用于衡量治疗效果。