Taieb A
Service de Dermatologie, Hôpital des Enfants, Bordeaux.
Ann Dermatol Venereol. 1990;117 Suppl 1:15-9.
Oxatomide is an antiallergic molecule which acts mainly as a calcium blocker. This article is a review of oxatomide treatment in atopic dermatitis patients. First, an overview of oxatomide treatment hypersensitivity reactions in atopic dermatitis and of their supposed immunologic mechanisms. The total number of patients treated so far in published studies is too low to fully appreciate the therapeutic benefit of this molecule. However, encouraging results were reported in two controlled studies and 3 open studies originating from four different groups. Tolerance was excellent (of 200 patients evaluated in 5 studies, transient sleepiness was noted in 5, and weight gain was noted in 3 children).
奥沙米特是一种主要作为钙阻滞剂起作用的抗过敏分子。本文是对奥沙米特治疗特应性皮炎患者的综述。首先，概述奥沙米特治疗特应性皮炎中的超敏反应及其推测的免疫机制。迄今为止，已发表研究中接受治疗的患者总数过低，无法充分认识到该分子的治疗益处。然而，四项不同研究小组开展的两项对照研究和三项开放性研究报告了令人鼓舞的结果。耐受性良好（在五项研究中评估的200名患者中，5人出现短暂嗜睡，3名儿童出现体重增加）。
