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组胺是蟋蟀听觉中间神经元ON1的抑制性递质的证据。

Evidence that histamine is the inhibitory transmitter of the auditory interneuron ON1 of crickets.

作者信息

Skiebe P, Corrette B J, Wiese K

机构信息

Zoologisches Institut, Universität Hamburg, F.R.G.

出版信息

Neurosci Lett. 1990 Aug 24;116(3):361-6. doi: 10.1016/0304-3940(90)90102-f.

DOI:10.1016/0304-3940(90)90102-f
PMID:1978745
Abstract

The omega neurons of crickets are connected with each other by reciprocal inhibition. This inhibition could be mimicked by bath-applied histamine and blocked by histamine H1-antagonists. Histamine, like ON1, also influenced the ascending interneuron AN2, so that its response pattern more closely reflected the temporal structure of the calling song. This evidence strongly suggests that histamine is the inhibitory transmitter of the ON1s.

摘要

蟋蟀的ω神经元通过相互抑制相互连接。这种抑制作用可被浴加组胺模拟,并被组胺H1拮抗剂阻断。组胺与ON1一样,也影响上行中间神经元AN2,使其反应模式更紧密地反映求偶鸣叫的时间结构。这一证据有力地表明,组胺是ON1的抑制性递质。

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