Rahimi-Rad Mohammad Hossein, Ilkhanizadeh Behrouz
Department of Internal Medicine, Faculty of Medicine, Urmia University, Urmia, West Azerbaijan, Iran.
Tuberk Toraks. 2009;57(3):333-6.
Endobronchial metastasis (EBM) is uncommon and frequently is seen in renal, breast, and colorectal carcinomas. Other reported primary tumors include melanoma, sarcomas, and tumors of the uterine cervix, testis, ovary, prostate, thyroid, pancreas, and adrenal glands. With reviewing the literature, we were able to find only one report of EBM from fibrosarcoma (in Spanish). We described a 56-year-old woman with EBM of oral fibrosarcoma with local recurrence 13 years after treatment of primary tumor. We conclude that the possibility of central airway metastasis should be kept in mind if patients with a past history of malignancy present with symptoms consistent with bronchial tumors, even if there are 13 years interval. Of several mechanisms EBM, we assume direct aspiration and implantation of tumor cells to bronchus from oral cancer.
支气管内转移(EBM)并不常见,常见于肾癌、乳腺癌和结直肠癌。其他报道的原发肿瘤包括黑色素瘤、肉瘤以及子宫颈、睾丸、卵巢、前列腺、甲状腺、胰腺和肾上腺的肿瘤。通过查阅文献,我们仅找到一篇关于纤维肉瘤支气管内转移的报道(西班牙语)。我们描述了一名56岁女性,患有口腔纤维肉瘤支气管内转移,在原发肿瘤治疗13年后出现局部复发。我们得出结论,如果有恶性肿瘤病史的患者出现与支气管肿瘤相符的症状,即使间隔了13年,也应考虑中央气道转移的可能性。在支气管内转移的几种机制中,我们推测肿瘤细胞是从口腔癌直接吸入并植入支气管的。