Hanigan W C, Asner N G, Elwood P W
Department of Neurosciences, University of Illinois College of Medicine, Peoria 61656-1649.
Surg Neurol. 1990 Dec;34(6):408-13. doi: 10.1016/0090-3019(90)90245-k.
This report describes three patients with spinal epidural abscess diagnosed by magnetic resonance imaging and treated nonoperatively. Prior to treatment, one patient was neurologically intact, one patient demonstrated a moderate neurological deficit, and one patient was severely paraparetic with loss of bladder and bowel control. Following identification of the pathogenic organism, antibiotic therapy was continued until the patients demonstrated clinical improvement and radiological resolution of the abscess. All patients remained stable or improved neurologically. Analysis of 33 previously reported patients treated with antibiotics suggests that nonoperative treatment may be a reasonable alternative therapy under certain clinical conditions. These include (1) identification of the pathogenic organism, (2) a stable neurological condition, (3) access to magnetic resonance imaging or computed tomography for potentially rapid reevaluation, and (4) appropriate neurosurgical consultation and nursing care. Nonoperative treatment may also be considered as a reasonable alternative for patients who have severe concurrent medical illness.
本报告描述了3例经磁共振成像诊断为脊髓硬膜外脓肿并接受非手术治疗的患者。治疗前,1例患者神经功能正常,1例患者有中度神经功能缺损,1例患者严重截瘫,伴有膀胱和肠道控制功能丧失。在确定病原体后,继续进行抗生素治疗,直到患者临床症状改善且脓肿影像学消退。所有患者神经功能保持稳定或改善。对33例先前报道的接受抗生素治疗的患者进行分析表明,在某些临床情况下,非手术治疗可能是一种合理的替代疗法。这些情况包括:(1)确定病原体;(2)神经功能状况稳定;(3)可进行磁共振成像或计算机断层扫描以便可能进行快速重新评估;(4)适当的神经外科会诊和护理。对于患有严重合并内科疾病的患者,非手术治疗也可被视为一种合理的替代方案。