Otolaryngology/Head and Neck Surgery, University of Southern California, Los Angeles, California, USA.
Head Neck. 2010 Jun;32(6):800-5. doi: 10.1002/hed.21237.
Oncocytoma is a rare, benign salivary neoplasm composed of mitochondria-rich cells called oncocytes. Although oncocytoma usually occurs in the parotid glands, it has much less commonly been reported to occur in minor salivary gland tissues. Although there have been a few reported cases of oncocytomas being found in the parapharyngeal space, most if not all cases seem to be extensions of deep lobe parotid tumors. We present a case of a 73-year-old man with a previous history of prostate cancer that had the incidental finding of an (18)F-fluorodeoxyglucose (FDG) image of a highly avid parapharyngeal space lesion noted on a follow-up positron emission tomography-computed tomography (PET/CT) scan. Excision of the mass, through a transcervical approach, demonstrated it to be an isolated oncocytoma of the parapharyngeal space, noncontiguous with the parotid gland. Based on our literature search, this may be the first such reported case. A brief review of the available literature examining the known body of knowledge regarding these neoplasms is presented.
闰细胞癌是一种罕见的良性唾液腺肿瘤，由富含线粒体的细胞组成，称为闰细胞。尽管闰细胞瘤通常发生在腮腺，但在小唾液腺组织中也较少见。尽管已有少数报告称咽旁间隙存在闰细胞瘤，但如果不是全部，大多数似乎都是腮腺深叶肿瘤的延伸。我们报告了一例 73 岁男性的病例，该患者有前列腺癌病史，在后续正电子发射断层扫描-计算机断层扫描 (PET/CT) 扫描上偶然发现咽旁间隙高度摄取的（18）F-氟脱氧葡萄糖 (FDG) 图像。通过经颈入路切除该肿块，证实为孤立的咽旁间隙闰细胞瘤，与腮腺无连续。根据我们的文献检索，这可能是首例此类报道。本文简要回顾了有关这些肿瘤的现有文献，以了解已知的知识体系。
