Lü De-Jian, Lu Hui-Ling
Department of Forensic Biology, Zhongshan Medical College of Sun Yat-sen University, Guangzhou 510089, China.
Fa Yi Xue Za Zhi. 2009 Aug;25(4):271-3.
To introduce a new method for calculating the paternity index (PI).
Assuming that each allele from parents has undergone a transition before it segregates and transmits to child. The transition probability is 1 when parent allele is the same as child's, the transition probability is 0 when parent allele is different from the child's. Every allele has a transmission probability with 0.5. Base on these theories, it is easy to gain the probability that child inherits an allele from the alleged father or mother. Thus, the X value (numerator) and Y value (denominator) of PI formula can be calculated, as unknown man provide an allele for child with the allele frequency.
A general formula that calculated the PI for trios, duos and missing child cases was deduced.
The new method is practical in all kinds of forensic paternity case.
介绍一种计算父权指数(PI)的新方法。
假设父母的每个等位基因在分离并传递给孩子之前都经历了一次转变。当父本等位基因与孩子的相同时,转变概率为1;当父本等位基因与孩子的不同时,转变概率为0。每个等位基因都有0.5的传递概率。基于这些理论,很容易得到孩子从被指控的父亲或母亲那里继承一个等位基因的概率。因此,可以计算PI公式的X值(分子)和Y值(分母),因为未知男子为孩子提供了一个具有等位基因频率的等位基因。
推导了一个计算三联体、二联体和失踪儿童案件PI的通用公式。
新方法在各类法医亲子鉴定案件中具有实用性。