Motosugi Utaroh, Ichikawa Tomoaki, Yamaguchi Hiroshi, Nakazawa Tadao, Katoh Ryohei, Itakura Jun, Fujii Hideki, Sato Tadashi, Araki Tsutomu, Shimizu Michio
Department of Radiology, University of Yamanashi, Chuo, Japan.
Pathol Int. 2009 Oct;59(10):744-7. doi: 10.1111/j.1440-1827.2009.02437.x.
An asymptomatic 59-year-old man underwent pancreatoduodenectomy for a pancreatic mass that was discovered during a health check-up. Histopathology indicated typical features of lymphoplasmacytic sclerosing pancreatitis (LPSP) or autoimmune pancreatitis along with the presence of abundant IgG4-positive plasma cells throughout the mass. A small invasive ductal adenocarcinoma was observed in the center of the area affected by LPSP. The present case suggests that LPSP may be closely related to carcinogenesis of the pancreas.
一名59岁无症状男性因在健康检查中发现胰腺肿块而接受了胰十二指肠切除术。组织病理学显示为淋巴细胞浆细胞性硬化性胰腺炎（LPSP）或自身免疫性胰腺炎的典型特征，且整个肿块中存在大量IgG4阳性浆细胞。在LPSP累及区域的中心观察到一个小的浸润性导管腺癌。本病例提示LPSP可能与胰腺癌的发生密切相关。
