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Hepatitis: Monitoring drug therapy for hepatitis B--a global challenge?

作者信息

Nguyen Tin, Locarnini Stephen

机构信息

Department of Gastroenterology, St Vincent's Hospital, Victoria, Australia.

出版信息

Nat Rev Gastroenterol Hepatol. 2009 Oct;6(10):565-7. doi: 10.1038/nrgastro.2009.160.

DOI:10.1038/nrgastro.2009.160
PMID:19789570
Abstract
摘要

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本文引用的文献

1
Baseline characteristics and early on-treatment response predict the outcomes of 2 years of telbivudine treatment of chronic hepatitis B.基线特征和早期治疗反应可预测替比夫定治疗慢性乙型肝炎2年的疗效。
J Hepatol. 2009 Jul;51(1):11-20. doi: 10.1016/j.jhep.2008.12.019. Epub 2009 Feb 12.
2
Hepatitis B virus surface antigen levels: a guide to sustained response to peginterferon alfa-2a in HBeAg-negative chronic hepatitis B.乙肝病毒表面抗原水平:HBeAg阴性慢性乙型肝炎患者对聚乙二醇干扰素α-2a持续应答的指标
Hepatology. 2009 Apr;49(4):1141-50. doi: 10.1002/hep.22760.
3
Long-term monitoring shows hepatitis B virus resistance to entecavir in nucleoside-naïve patients is rare through 5 years of therapy.
乙型肝炎病毒在肝细胞中持续存在的机制及其致癌潜力
Clin Infect Dis. 2016 Jun 1;62 Suppl 4(Suppl 4):S281-8. doi: 10.1093/cid/ciw023.
4
Serum proteins in chronic hepatitis B patients treated with peginterferon alfa-2b.聚乙二醇干扰素 alfa-2b 治疗慢性乙型肝炎患者的血清蛋白。
World J Gastroenterol. 2013 Aug 21;19(31):5067-75. doi: 10.3748/wjg.v19.i31.5067.
5
Phase diagrams map the properties of antiviral agents directed against hepatitis B virus core assembly.相图描绘了针对乙型肝炎病毒核心组装的抗病毒药物的特性。
Antimicrob Agents Chemother. 2013 Mar;57(3):1505-8. doi: 10.1128/AAC.01766-12. Epub 2012 Dec 3.
长期监测显示,初治患者在接受5年恩替卡韦治疗期间,对该药物产生乙肝病毒耐药的情况罕见。
Hepatology. 2009 May;49(5):1503-14. doi: 10.1002/hep.22841.
4
EASL Clinical Practice Guidelines: management of chronic hepatitis B.欧洲肝脏研究学会临床实践指南:慢性乙型肝炎的管理
J Hepatol. 2009 Feb;50(2):227-42. doi: 10.1016/j.jhep.2008.10.001. Epub 2008 Oct 29.
5
HBeAg and hepatitis B virus DNA as outcome predictors during therapy with peginterferon alfa-2a for HBeAg-positive chronic hepatitis B.聚乙二醇干扰素α-2a治疗HBeAg阳性慢性乙型肝炎期间,HBeAg和乙肝病毒DNA作为疗效预测指标
Hepatology. 2008 Feb;47(2):428-34. doi: 10.1002/hep.22065.
6
Predicting response to peginterferon alpha-2a, lamivudine and the two combined for HBeAg-negative chronic hepatitis B.预测聚乙二醇干扰素α-2a、拉米夫定及两者联合用药对HBeAg阴性慢性乙型肝炎的疗效
Gut. 2007 May;56(5):699-705. doi: 10.1136/gut.2005.089722. Epub 2006 Nov 24.
7
Predicting cirrhosis risk based on the level of circulating hepatitis B viral load.基于循环乙肝病毒载量水平预测肝硬化风险。
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Risk of hepatocellular carcinoma across a biological gradient of serum hepatitis B virus DNA level.血清乙型肝炎病毒DNA水平生物梯度上肝细胞癌的风险。
JAMA. 2006 Jan 4;295(1):65-73. doi: 10.1001/jama.295.1.65.
9
Lamivudine for patients with chronic hepatitis B and advanced liver disease.拉米夫定用于慢性乙型肝炎和晚期肝病患者。
N Engl J Med. 2004 Oct 7;351(15):1521-31. doi: 10.1056/NEJMoa033364.