Rafat Marjan, Raad Danielle R, Rowat Amy C, Auguste Debra T
School of Engineering and Applied Sciences, Harvard University, Cambridge, MA 02138, USA.
Lab Chip. 2009 Oct 21;9(20):3016-9. doi: 10.1039/b907957b. Epub 2009 Jul 22.
Fluidic devices are often made by irreversibly bonding a polydimethylsiloxane (PDMS) mold to itself or a glass substrate by plasma treatment. This method limits the range of materials for fluidic device fabrication and utility for subsequent processing. Here, we present a simple and inexpensive method to fabricate fluidic devices using magnets to reversibly adhere PDMS and other polymer matrices to glass or gel substrates. This approach enables fluidic devices to be fabricated from a variety of materials other than PDMS and glass. Moreover, this method can be used to fabricate composite devices, three-dimensional scaffolds and hydrogel-based fluidic devices.
流体装置通常通过等离子体处理将聚二甲基硅氧烷(PDMS)模具不可逆地粘结到自身或玻璃基板上来制造。这种方法限制了用于流体装置制造的材料范围以及后续加工的实用性。在此,我们提出一种简单且廉价的方法来制造流体装置,即使用磁铁将PDMS和其他聚合物基质可逆地粘附到玻璃或凝胶基板上。这种方法能够使用除PDMS和玻璃之外的多种材料来制造流体装置。此外,该方法可用于制造复合装置、三维支架和基于水凝胶的流体装置。