Division of Cardiology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
J Cardiovasc Electrophysiol. 2010 Jan;21(1):27-32. doi: 10.1111/j.1540-8167.2009.01593.x. Epub 2009 Sep 28.
Early recurrence of atrial tachyarrhythmias is commonly noted after catheter ablation of atrial fibrillation (AF). The long-term outcomes of patients who require cardioversion for persistent AF after AF ablation is not known. This study reports the outcomes of patients who underwent cardioversion for persistent AF or atrial flutter following an AF ablation procedure.
The patient population comprised 55 patients (mean age 58 +/- 10 years, 35% paroxysmal) who underwent catheter ablation of AF and subsequently required electrical cardioversion for persistent AF (45 patients) or atrial flutter (10 patients). Cardioversion was defined as early (within 90 days of the ablation procedure) or late (between 90 and 180 days following ablation).
The mean follow-up duration was 15 +/- 8 months. Forty-six of the 55 patients (84%) patients experienced recurrence during follow-up. The average time to recurrence after cardioversion was 37 days. Of the 55 patients, 8 (15%) patients had a complete success, 11 (20%) patients had a partial success and 36 patients (65%) had a failed outcome. Seven of the 43 patients (16%) who underwent early cardioversion had a complete success as opposed to one of 12 patients (8%) who underwent late cardioversion (P = 0.49).
This study shows that >80% of patients who undergo cardioversion for persistent AF or atrial flutter after AF ablation have recurrence. The timing of cardioversion did not affect the outcome. These findings allow clinicians to provide realistic expectations to patients regarding the long-term outcome and/or requirement for a second ablation procedure.
心房颤动(AF)消融后常早期复发房性心动过速。AF 消融后持续性 AF 需要电复律患者的长期结果尚不清楚。本研究报告了 AF 消融后持续性 AF 或房扑行电复律患者的结局。
患者人群包括 55 例(平均年龄 58 +/- 10 岁,35%为阵发性)行 AF 消融后需行电复律的患者,持续性 AF(45 例)或房扑(10 例)。电复律定义为早期(消融术后 90 天内)或晚期(消融术后 90-180 天)。
平均随访时间为 15 +/- 8 个月。55 例患者中有 46 例(84%)在随访期间复发。电复律后复发的平均时间为 37 天。55 例患者中,8 例(15%)完全成功,11 例(20%)部分成功,36 例(65%)失败。43 例早期电复律患者中有 7 例(16%)完全成功,而 12 例晚期电复律患者中有 1 例(8%)成功(P = 0.49)。
本研究表明,AF 消融后行持续性 AF 或房扑电复律的患者中>80%复发。电复律时机不影响结局。这些发现使临床医生能够向患者提供关于长期结局和/或需要二次消融的现实期望。