Tillman Julie A, Raff Gregory J
Department of Obstetrics and Gynecology, Indiana University School of Medicine, Indianapolis, 46202, USA.
JSLS. 2009 Jul-Sep;13(3):433-5.
Paraneoplastic syndromes are a heterogeneous collection of disease manifestations caused by underlying neoplasms, which can include adnexal masses.
We report a case of paraneoplastic limbic encephalitis consisting of confusion, agitation, and aggression, which subsequently progressed to a comatose state, in the presence of an adnexal mass. It was cured with resection of a mature teratoma with focal immature components.
Female patients who present with symptoms of limbic encephalitis should be thoroughly screened for malignancy. Gynecologic consultation is an important component of the diagnostic workup when an adnexal mass has been identified. Paraneoplastic limbic encephalitis is a serious condition, yet it has a good prognosis if treated promptly with surgical resection of the adnexal mass.
副肿瘤综合征是由潜在肿瘤引起的一组异质性疾病表现，其中可能包括附件肿块。
我们报告一例副肿瘤性边缘叶脑炎病例，患者表现为意识模糊、烦躁不安和攻击性，随后发展为昏迷状态，同时存在附件肿块。通过切除含有局灶性未成熟成分的成熟畸胎瘤，患者得以治愈。
出现边缘叶脑炎症状的女性患者应全面筛查恶性肿瘤。当发现附件肿块时，妇科会诊是诊断检查的重要组成部分。副肿瘤性边缘叶脑炎是一种严重疾病，但如果及时通过手术切除附件肿块进行治疗，预后良好。
