NorthShore University HealthSystem, Department of Pathology and Laboratory Medicine, 2650 Ridge Avenue, Evanston, IL 60201, USA.
J Clin Microbiol. 2009 Nov;47(11):3749-52. doi: 10.1128/JCM.01223-08. Epub 2009 Sep 30.
Our three-hospital system began active surveillance for methicillin-resistant Staphylococcus aureus (MRSA) nasal colonization, with decolonization of positive patients, on all admissions starting 1 August 2005. A question not previously addressed is whether reduction of the incidence of MRSA disease would lower the total number of S. aureus clinical isolates recovered by the microbiology laboratory that are reported to health care providers. The decreases in the numbers of MRSA and total S. aureus clinical isolates for each year after August 2005 were highly statistically significant compared to the numbers in each of the prior 3 years (P < 0.0001).
我们的三所医院系统从 2005 年 8 月 1 日开始对所有入院患者进行耐甲氧西林金黄色葡萄球菌(MRSA)鼻腔定植的主动监测,并对定植阳性患者进行去定植。此前尚未解决的一个问题是,降低 MRSA 疾病的发病率是否会降低微生物实验室报告给医疗机构的金黄色葡萄球菌临床分离株的总数。与前 3 年的数量相比,2005 年 8 月后每年的 MRSA 和总金黄色葡萄球菌临床分离株数量均有显著统计学意义(P < 0.0001)。