Ruzić Klementina, Dadić-Hero Elizabeta, Knez Rajna, Medved Paola, Petrić Daniela
University Psychiatric Clinic Rijeka, Clinical Hospital Centre Rijeka, Rijeka, Croatia.
Psychiatr Danub. 2009 Sep;21(3):368-70.
Scientific research aiming at discovering new generations of effective medications is a common practice in medicine, and psychiatric research is no exception. Antipsychotics are used to treat chronic mental illnesses such as schizophrenia. The new generation of antipsychotics (atypicals) gradually reveal their advantages in comparison to the older generation of antipsychotics (conventional, typicals) and are increasingly applied to the everyday practice. Although there are no differences in the therapeutic effectiveness between the two groups mentioned, atypical antipsychotics have become the drugs of choice. A certain number of women in their reproductive age suffer from schizophrenia and other mental illnesses which demand antipsychotic treatment. Atypical antipsychotics have been available on the market since the mid 90's so the experience in the application of these medicaments in treating pregnant women is relatively modest. This study will present our own experience in the treatment of a pregnant woman suffering from schizophrenia, who was treated with ziprasidone for the duration of her pregnancy. The psychotic symptoms remained in remission throughout the whole pregnancy period, during labour and after the birth. The pregnancy course remained normal all through to the birth, which was carried out naturally and normally. A healthy baby was born within the term expected.
旨在发现新一代有效药物的科学研究在医学领域是常见做法，精神病学研究也不例外。抗精神病药物用于治疗诸如精神分裂症等慢性精神疾病。与老一辈抗精神病药物（传统的、典型的）相比，新一代抗精神病药物（非典型药物）逐渐展现出其优势，并越来越多地应用于日常医疗实践中。尽管上述两组药物在治疗效果上并无差异，但非典型抗精神病药物已成为首选药物。一定数量处于育龄期的女性患有精神分裂症和其他需要抗精神病治疗的精神疾病。自20世纪90年代中期以来，非典型抗精神病药物已投放市场，因此在治疗孕妇时使用这些药物的经验相对较少。本研究将介绍我们治疗一名患有精神分裂症孕妇的自身经验，该孕妇在整个孕期都使用齐拉西酮进行治疗。在整个孕期、分娩期间及产后，精神病症状一直处于缓解状态。整个孕期过程直至分娩都保持正常，分娩自然且顺利。在预期孕周内诞下一名健康婴儿。
