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[压力的意义:其在听觉系统中的作用及耳鸣的发病机制]

[The significance of stress: its role in the auditory system and the pathogenesis of tinnitus].

作者信息

Mazurek B, Stöver T, Haupt H, Klapp B F, Adli M, Gross J, Szczepek A J

机构信息

HNO-Klinik und Poliklinik, Tinnituszentrum und molekularbiologisches Forschungslabor, Charité-Universitätsmedizin Berlin, Campus Charité Mitte, Berlin, Deutschland.

出版信息

HNO. 2010 Feb;58(2):162-72. doi: 10.1007/s00106-009-2001-5.

Abstract

Emotional stress is often associated with auditory phenomena such as hyperacusis, tinnitus, Ménière's disease and vertigo. Stress develops as a result of a person's attempts to come to terms with the increased or unexpected demands of his or her environment. Stress serves to protect one from physical danger and to temporarily increase one's performance in order to increase the probability of survival. Sleep and appetite are particularly reduced, while anxiety increases. The mental changes induced by stress may contribute to the onset or exacerbation of tinnitus. The following links exist between the auditory and stress systems: the limbic system, which regulates instinctive behavior and emotions, is linked to the auditory system via the medial geniculate body (amygdala). The hypothalamus, which is the integrative center of the endocrine and autonomic systems, is linked to the auditory system via the inferior colliculus. The reticular system, which is focused on the behavior pattern of attention and excitement, projects serotonergic fibers to all pathways of the auditory system, ranging from the cochlea to the auditory cortex.

摘要

情绪应激常与听觉现象相关,如听觉过敏、耳鸣、梅尼埃病和眩晕。应激是由于个体试图应对其所处环境增加的或意外的要求而产生的。应激有助于保护个体免受身体危险,并暂时提高其表现,以增加生存几率。睡眠和食欲会特别减少,而焦虑则会增加。应激引起的心理变化可能导致耳鸣的发作或加重。听觉系统和应激系统之间存在以下联系:调节本能行为和情绪的边缘系统通过内侧膝状体(杏仁核)与听觉系统相连。下丘脑是内分泌和自主神经系统的整合中心,通过下丘与听觉系统相连。专注于注意力和兴奋行为模式的网状系统将血清素能纤维投射到听觉系统的所有通路,从耳蜗到听觉皮层。

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