Department of Physical Medicine and Rehabilitation, ZNA Middelheim, Lindendreef 1, 2020, Antwerp, Belgium.
Clin Rheumatol. 2010 Jan;29(1):115-7. doi: 10.1007/s10067-009-1289-6. Epub 2009 Oct 1.
We report the case of a 55-year-old male with flexion contractures of the hips and the knees due to an isolated adrenocorticotropin (ACTH) deficiency, a rare cause of secondary adrenal insufficiency. The presenting symptoms and signs, the laboratory investigations and the treatment are described. The case description is followed by a brief overview of ACTH deficiency and its symptoms and causes. Our case is then compared with other case reports available in the literature. The aetiology of the flexion contractures in adrenal insufficiency is still unclear. The authors want to draw attention to adrenal insufficiency as the cause of unexplained flexion contractures.
我们报告了一例 55 岁男性,因孤立性促肾上腺皮质激素(ACTH)缺乏症导致髋关节和膝关节弯曲挛缩,这是继发性肾上腺功能不全的罕见原因。描述了其表现症状、实验室检查和治疗。病例描述后简要概述了 ACTH 缺乏症及其症状和病因。然后将我们的病例与文献中其他病例报告进行了比较。肾上腺功能不全时发生弯曲挛缩的病因仍不清楚。作者希望提醒大家注意肾上腺功能不全是导致不明原因弯曲挛缩的原因。