一例经活检证实的心肌炎进展为经尸检证实的扩张型心肌病。

A case of biopsy-proven myocarditis progressing to autopsy-proven dilated cardiomyopathy.

作者信息

Matoba Y, Matsumori A, Ohtani H, Tominaga M, Fujiwara H, Toyokuni S, Takahashi K, Midorikawa O, Kawai C

机构信息

Department of Internal Medicine, Kyoto University, Japan.

出版信息

Clin Cardiol. 1990 Oct;13(10):732-7. doi: 10.1002/clc.4960131013.

DOI:10.1002/clc.4960131013

PMID:1979528

Abstract

A 22-year-old man presented with congestive heart failure following flulike symptoms. The diagnosis of acute myocarditis was confirmed by endomyocardial biopsy, which revealed mild infiltration of inflammatory cells. A favorable response to beta-adrenergic receptor blockade was seen, and the patient was discharged without symptoms. Five months later, however, congestive heart failure recurred, and intracardiac thrombi were demonstrated. The patient died after two months. Postmortem examination revealed left ventricular dilatation with slight interstitial fibrosis; the diagnosis was dilated cardiomyopathy. Thus, progression of biopsy-proven myocarditis to dilated cardiomyopathy 10 months after the onset of disease was documented.

摘要

一名22岁男性在出现流感样症状后出现充血性心力衰竭。心内膜心肌活检证实为急性心肌炎，显示有轻度炎性细胞浸润。患者对β-肾上腺素能受体阻滞剂反应良好，出院时无症状。然而，五个月后，充血性心力衰竭复发，并发现心内血栓形成。两个月后患者死亡。尸检显示左心室扩张，伴有轻微间质纤维化；诊断为扩张型心肌病。因此，记录了疾病发作10个月后活检证实的心肌炎进展为扩张型心肌病的情况。