Department of Clinical Neurological Sciences, London Health Sciences Centre, London, Ontario, Canada.
Mov Disord. 2009 Nov 15;24(15):2199-202. doi: 10.1002/mds.22549.
Lingual movement disorders are a rare but serious manifestation of neurologic disease, which have the potential to cause significant morbidity. Traditionally, these disorders were treated with pharmacotherapy achieving only limited results. Several case series have demonstrated the effectiveness of Botulinum toxin injection for the management of focal lingual movement disorders; however, apprehension persists regarding intralingual injections due to the risk of dysphagia. Here, we report seven patients with lingual movement disorders treated with intralingual Botox (Allergan product) injections via a novel superior approach into the genioglossus over a period of 3 to 72 months. All patients experienced a marked improvement in their abnormal tongue movements with no substantial bleeding or dysphagia. Lingual Botulinum toxin injection should be considered a safe and viable treatment option for a variety of disorders affecting the tongue.
语言运动障碍是一种罕见但严重的神经疾病表现，可能导致严重的发病率。传统上，这些疾病通过药物治疗来治疗，只能取得有限的效果。有几个病例系列已经证明了肉毒杆菌毒素注射治疗局灶性舌运动障碍的有效性；然而，由于吞咽困难的风险，对于舌内注射仍然存在担忧。在这里，我们报告了 7 例通过一种新的改良颏舌肌上入路，在 3 至 72 个月的时间内，对舌运动障碍患者进行舌内注射肉毒杆菌毒素（Allergan 产品）的治疗。所有患者的异常舌运动均明显改善，无明显出血或吞咽困难。舌部肉毒杆菌毒素注射应被视为一种安全可行的治疗选择，可用于治疗多种影响舌部的疾病。
