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肉毒毒素治疗口颌面部肌张力障碍和口腔颌面部运动障碍。

Botulinum Toxin Therapy for Oromandibular Dystonia and Other Movement Disorders in the Stomatognathic System.

机构信息

Department of Oral and Maxillofacial Surgery, National Hospital Organization, Kyoto Medical Center, 1-1 Mukaihata-cho, Fukakusa, Fushimi-ku, Kyoto 612-8555, Japan.

出版信息

Toxins (Basel). 2022 Apr 14;14(4):282. doi: 10.3390/toxins14040282.

Abstract

Various movement disorders, such as oromandibular dystonia, oral dyskinesia, bruxism, functional (psychogenic) movement disorder, and tremors, exist in the stomatognathic system. Most patients experiencing involuntary movements due to these disorders visit dentists or oral surgeons, who may be the first healthcare providers. However, differential diagnoses require neurological and dental knowledge. This study aimed to review scientific advances in botulinum toxin therapy for these conditions. The results indicated that botulinum toxin injection is effective and safe, with few side effects in most cases when properly administered by an experienced clinician. The diagnosis and treatment of movement disorders in the stomatognathic system require both neurological and dental or oral surgical knowledge and skills, and well-designed multicenter trials with a multidisciplinary team approach must be necessary to ensure accurate diagnosis and proper treatment.

摘要

口腔颌面部系统中存在各种运动障碍,如口颌肌张力障碍、口腔运动障碍、磨牙症、功能性(心因性)运动障碍和震颤等。大多数因这些障碍而出现不自主运动的患者会去看牙医或口腔外科医生,他们可能是第一批医疗保健提供者。然而,鉴别诊断需要神经学和牙科知识。本研究旨在综述这些疾病的肉毒毒素治疗的科学进展。结果表明,在经验丰富的临床医生正确施药的情况下,大多数情况下,肉毒毒素注射是有效且安全的,副作用较少。口腔颌面部系统运动障碍的诊断和治疗需要神经学和牙科或口腔外科学知识和技能,并且必须采用多学科团队方法进行精心设计的多中心试验,以确保准确诊断和适当治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e456/9026473/2d5f727a7887/toxins-14-00282-g001.jpg

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