评估颈部引流液和血清中的淀粉酶水平以早期诊断咽皮瘘。
Evaluation of amylase levels in the neck drainage and serum for early diagnosis of the pharyngocutaneous fistula.
作者信息
Kasapoğlu Fikret, Ozmen Omer Afşın, Coşkun Hakan, Erişen Levent, Onart Selçuk
机构信息
Department of Otolaryngology, Medicine Faculty of Uludağ University, Bursa, Turkey.
出版信息
Kulak Burun Bogaz Ihtis Derg. 2009 Mar-Apr;19(2):67-70.
OBJECTIVES
To assess the value of amylase levels in neck drainage and serum for the diagnosis of pharyngocutaneous fistula in the early postoperative period.
PATIENTS AND METHODS
We conducted a prospective study in a tertiary referral setting. Thirty-two patients (31 males, 1 female; mean age 63; range 45 to 75 years) who had laryngectomy operation as the primary treatment were studied. Amylase levels in the neck drainage and serum were analyzed in the first three postoperative days. The results were compared between patients who developed pharyngocutaneous fistula and who did not.
RESULTS
Serum amylase levels were significantly higher in pharyngocutaneous fistula group, whereas amylase in the neck drainage was not diagnostic.
CONCLUSION
Serum amylase levels may be used in laryngectomy patients for the early diagnosis of pharyngocutaneous fistula.
目的
评估颈部引流液和血清淀粉酶水平对喉切除术后早期咽皮瘘诊断的价值。
患者与方法
我们在一家三级转诊机构进行了一项前瞻性研究。研究对象为32例行喉切除术作为主要治疗手段的患者（31例男性，1例女性；平均年龄63岁；年龄范围45至75岁）。术后前三天分析颈部引流液和血清中的淀粉酶水平。比较发生咽皮瘘和未发生咽皮瘘的患者的结果。
结果
咽皮瘘组血清淀粉酶水平显著更高，而颈部引流液中的淀粉酶无诊断价值。
结论
血清淀粉酶水平可用于喉切除患者咽皮瘘的早期诊断。
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