抗瓜氨酸化蛋白/肽抗体和类风湿因子：两个不同的自身抗体系统。
Anticitrullinated protein/peptide antibodies and rheumatoid factors: two distinct autoantibody systems.
出版信息
Arthritis Res Ther. 2009;11(5):125. doi: 10.1186/ar2786. Epub 2009 Sep 14.
Abstract
In a previous issue of Arthritis Research and Therapy, Ursum and colleagues report the relative stabilities of anticitrullinated protein/peptide antibodies (ACPAs) and IgM rheumatoid factors during the course of rheumatoid arthritis and their differential correlation with markers of the acute-phase response. These findings add to a growing body of evidence highlighting the distinct nature of these two autoantibody systems and the role of ACPAs as a disease-specific marker of rheumatoid arthritis.
摘要
在《关节炎研究与治疗》的前一期中，Ursum 及其同事报告了抗瓜氨酸化蛋白/肽抗体（ACPA）和 IgM 类风湿因子在类风湿关节炎病程中的相对稳定性，以及它们与急性期反应物标记物的差异相关性。这些发现增加了越来越多的证据，强调了这两种自身抗体系统的独特性质，以及 ACPA 作为类风湿关节炎特异性疾病标志物的作用。
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本文引用的文献
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J Rheumatol. 2009 Apr;36(4):706-11. doi: 10.3899/jrheum.080895. Epub 2009 Feb 17.
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