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生命科学中术语资源的再利用对于有效的本体工程学至关重要。

Reuse of terminological resources for efficient ontological engineering in Life Sciences.

机构信息

European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, CB10 1SD, UK.

出版信息

BMC Bioinformatics. 2009 Oct 1;10 Suppl 10(Suppl 10):S4. doi: 10.1186/1471-2105-10-S10-S4.

DOI:10.1186/1471-2105-10-S10-S4
PMID:19796401
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2755825/
Abstract

This paper is intended to explore how to use terminological resources for ontology engineering. Nowadays there are several biomedical ontologies describing overlapping domains, but there is not a clear correspondence between the concepts that are supposed to be equivalent or just similar. These resources are quite precious but their integration and further development are expensive. Terminologies may support the ontological development in several stages of the lifecycle of the ontology; e.g. ontology integration. In this paper we investigate the use of terminological resources during the ontology lifecycle. We claim that the proper creation and use of a shared thesaurus is a cornerstone for the successful application of the Semantic Web technology within life sciences. Moreover, we have applied our approach to a real scenario, the Health-e-Child (HeC) project, and we have evaluated the impact of filtering and re-organizing several resources. As a result, we have created a reference thesaurus for this project, named HeCTh.

摘要

本文旨在探讨如何使用术语资源进行本体工程。如今,有几个描述重叠领域的生物医学本体,但假定等价或相似的概念之间并没有明确的对应关系。这些资源非常宝贵,但它们的集成和进一步开发成本很高。术语学可以在本体的生命周期的几个阶段支持本体的开发;例如,本体集成。在本文中,我们研究了在本体生命周期中术语资源的使用。我们声称,创建和使用共享词库是成功应用语义 Web 技术在生命科学中的基石。此外,我们已经将我们的方法应用于一个真实的场景,即健康儿童(HeC)项目,并评估了过滤和重新组织几个资源的影响。结果,我们为该项目创建了一个参考词库,命名为 HeCTh。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eb0e/2755825/3558b96fa0a0/12859_2009_Article_3372_Fig6_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eb0e/2755825/5b3f0bcbc5ca/12859_2009_Article_3372_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eb0e/2755825/370630c504f7/12859_2009_Article_3372_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eb0e/2755825/3e6c75c5eb44/12859_2009_Article_3372_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eb0e/2755825/30dadfd35980/12859_2009_Article_3372_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eb0e/2755825/8518ce3df71f/12859_2009_Article_3372_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eb0e/2755825/3558b96fa0a0/12859_2009_Article_3372_Fig6_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eb0e/2755825/5b3f0bcbc5ca/12859_2009_Article_3372_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eb0e/2755825/370630c504f7/12859_2009_Article_3372_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eb0e/2755825/3e6c75c5eb44/12859_2009_Article_3372_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eb0e/2755825/30dadfd35980/12859_2009_Article_3372_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eb0e/2755825/8518ce3df71f/12859_2009_Article_3372_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eb0e/2755825/3558b96fa0a0/12859_2009_Article_3372_Fig6_HTML.jpg

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