Maclean D, McDevitt D G
University Department of Clinical Pharmacology, Ninewells Hospital, Dundee, UK.
J Hum Hypertens. 1990 Oct;4 Suppl 3:50-1.
A study of doxazosin added to baseline therapy with a beta-adrenoceptor blocker plus a diuretic in the treatment of patients 'resistant' to the baseline therapy, showed that it was effective and generally well tolerated. The study was, however, open-label and lacked comparison with other third-line drugs.
一项关于在使用β-肾上腺素能受体阻滞剂加利尿剂的基础治疗上添加多沙唑嗪来治疗对基础治疗“抵抗”的患者的研究表明,该方法有效且耐受性普遍良好。然而,该研究为开放标签研究,且缺乏与其他三线药物的对比。