Holanda Fernanda R, Coelho-de-Sousa Andrelina N, Assreuy Ana M S, Leal-Cardoso José Henrique, Pires Alana F, do Nascimento Kyria S, Teixeira Cícero S, Cavada Benildo S, Santos Cláudia F
Instituto Superior de Ciências Biomédicas, Universidade Estadual do Ceará, Av. Paranjana, 1700, 60740-000, Fortaleza, Ceará, Brasil.
Protein Pept Lett. 2009;16(9):1088-92. doi: 10.2174/092986609789055304.
Diocleinae lectins administered per oral route in mice inhibited the abdominal constrictions induced by acetic acid. The percentage of the lectins antinociception varied from 61% for Canavalia grandiflora (ConGf) to 20% for Dioclea violacea. ConGf inhibited contortions at all doses tested but not in a dose-dependent manner, involving carbohydrate recognition.
经口服途径给予小鼠的双花豆亚科凝集素可抑制乙酸诱导的腹部收缩。凝集素抗伤害感受的百分比从大花刀豆（ConGf）的61%到紫花双花豆的20%不等。ConGf在所有测试剂量下均能抑制扭体反应，但并非呈剂量依赖性，这涉及碳水化合物识别。
