Hou Guo-Liang, Li Yong-Hong, Zhang Zhi-Ling, Xiong Yong-Hong, Chen Xiao-Feng, Yao Kai, Liu Zhuo-Wei, Han Hui, Qin Zi-Ke, Zhou Fang-Jian
State Key Laboratory of Oncology in Southern China, Guangzhou, People's Republic of China.
Urology. 2009 Nov;74(5):1145-9. doi: 10.1016/j.urology.2009.06.082. Epub 2009 Oct 2.
To introduce a modified technique for urethral anastomosis in orthotopic neobladder reconstruction.
Between January 2002 and August 2008, about 141 consecutive patients (130 men and 11 women) underwent total cystectomy and orthotopic neobladder reconstruction in which a modified technique was used to anastomosed the caudal-most part of the intestinal neobladder directly to the urethral remnant. The emptying of the neobladder, the early and late complications at the urethral anastomosis was evaluated.
Mean patient age at surgery was 58.4 years (range, 33-83) and median follow-up was 42 months (range, 4-83 months). Early urine leakage at the vesicourethral anastomosis developed in 1 patient, and was cured by extending catheter drainage. A total of 138 patients had good emptying of the neobladder, with residual urine volume < 50 mL. Three patients had residual urine volume > 100 mL, and achieved good emptying after intermittent catheterization once a week for 6-12 months. No late complications occurred at the urethral anastomosis site. Daytime continence was good or satisfactory in 97.0% of patients and night-time continence was good or satisfactory in 88.5% of patients.
The clinical outcome of our modified technique for urethral anastomosis in orthotopic neobladder substitution was excellent, but the advantage of this technique needs prospective controlled study.
介绍一种改良技术用于原位新膀胱重建术中的尿道吻合。
2002年1月至2008年8月,约141例连续患者(130例男性和11例女性)接受了全膀胱切除术和原位新膀胱重建术,术中采用改良技术将肠代新膀胱的最尾端部分直接与尿道残端进行吻合。评估新膀胱的排空情况以及尿道吻合处的早期和晚期并发症。
手术时患者的平均年龄为58.4岁(范围33 - 83岁),中位随访时间为42个月(范围4 - 83个月)。1例患者出现膀胱尿道吻合处早期漏尿,通过延长导尿管引流治愈。共有138例患者新膀胱排空良好,残余尿量<50 mL。3例患者残余尿量>100 mL,经每周1次间歇性导尿6 - 12个月后实现良好排空。尿道吻合部位未发生晚期并发症。97.0%的患者日间控尿良好或满意,88.5%的患者夜间控尿良好或满意。
我们改良的原位新膀胱替代术中尿道吻合技术的临床效果良好,但该技术的优势需要前瞻性对照研究。