Leibniz Institute for Natural Product Research and Infection Biology, Beutenbergstr. 11a, 07745 Jena, Germany.
Trends Microbiol. 2009 Dec;17(12):570-6. doi: 10.1016/j.tim.2009.09.003. Epub 2009 Oct 1.
Mycotoxins are compounds of fungal origin that can adversely affect human, animal and plant health through food spoilage or infection, even to the point of epidemics such as turkey X disease and ergotism. The biosynthetic pathways of various mycotoxins (such as aflatoxin and fumonisins) are generally well understood. However, two examples have recently been described where a mycotoxin is not synthesized by the fungus itself but by bacteria residing within the fungal cytosol. These discoveries have implications in various fields, such as ecology, medicine and food processing.
真菌毒素是真菌产生的化合物,通过食物腐败或感染,可对人类、动物和植物健康造成不良影响,甚至导致像火鸡 X 病和麦角中毒这样的流行病。各种真菌毒素(如黄曲霉毒素和伏马菌素)的生物合成途径通常都有很好的了解。然而,最近有两个例子表明,真菌本身并不合成真菌毒素,而是由生活在真菌胞质溶胶中的细菌合成的。这些发现对生态学、医学和食品加工等各个领域都有影响。