McCaughey Ryan G, Chlebicki Cara, Wong Brian J F
Beckman Laser Institute and Medical Clinic, University of California, Irvine, California 92612, USA.
Lasers Surg Med. 2010 Jan;42(1):69-75. doi: 10.1002/lsm.20856.
Laser light is known to stimulate nerves. This study investigated alternative wavelengths for nerve stimulation.
The sciatic nerves of rats were irradiated with four different lasers-a Ho:YAG (2100 nm), a Yb:glass fiber laser (1495 nm) and diode lasers (1450 nm and 1540 nm).
All lasers evoked a visible leg twitch response, and electromyography confirmed muscle activation. The Yb:glass laser at 1495 nm delivered through a single mode fiber was found to be the most effective stimulus. The stimulation threshold for a 2 millisecond pulse from the Yb:glass laser was determined to be 3.7+/-2.8 mJ/cm(2).
The Yb:glass laser has the potential for use in neurostimulation, as an alternative to electrical stimulation.
已知激光能刺激神经。本研究探究了用于神经刺激的其他波长。
用四种不同的激光照射大鼠的坐骨神经——钬激光（2100纳米）、镱玻璃光纤激光（1495纳米）和二极管激光（1450纳米和1540纳米）。
所有激光均引发了可见的腿部抽搐反应，且肌电图证实了肌肉激活。发现通过单模光纤传输的1495纳米镱玻璃激光是最有效的刺激源。来自镱玻璃激光的2毫秒脉冲的刺激阈值确定为3.7±2.8毫焦/平方厘米。
镱玻璃激光有潜力作为电刺激的替代物用于神经刺激。
