Dapper D V, Nwauche C A, Siminialayi I M
Department of Human Physiology, Faculty of Basic Medical Sciences, College of Health Sciences, University of Port Harcourt, Port Harcourt, Rivers State.
Niger J Clin Pract. 2009 Sep;12(3):262-7.
Published reports of haematological reference values for pre-primary and primary school aged residents of Port Harcourt, Nigeria are relatively scanty.
To determine the reference ranges of some haematological parameters for pre-primary and primary school aged children resident in Port Harcourt, Nigeria.
A total of 250 pre-primary school subjects consisting of 124 males and 126 females aged between 1 to 5 years and 536 primary school children consisting of 262 males and 274 females aged between 6 and 13 years resident in Port Harcourt, Nigeria were randomly recruited into the study. 3-5 ml of venous blood was collected with minimum stasis and the values of the following haematological parameters determined by the indicated methods: Haematocrit was determined using Hawksley micro-capillary tubes centrifuged at 3000 rpm for 10 minutes. Red blood cells, white blood cells [including a differential count] and platelet cells were counted manually using the improved Neubauer counting chamber. Erythrocyte Sedimentation Rate (ESR) was determined using the Westergren method. Haemoglobin concentration was determined by the cyanmethaemoglobin method.
The reference ranges for haematocrit, total white blood cell, differential neutrophils and lymphocyte counts, platelet cell counts and erythrocyte sedimentation rates; haemoglobin concentration and red cell counts are presented for male and female pre-primary and primary school children in Port Harcourt. There were no significant gender variations in the values of these parameters in both pre-primary and primary school children. However, primary school subjects, irrespective of sex, were found to have significantly higher values of lymphocyte differential counts and erythrocyte sedimentation rates and significantly lower platelet counts and total white cell counts and differential neutrophils counts compared to their pre-primary school counterparts [p<0.05]. There were no significant differences in the values of haematocrit between the two subject groups; though the values in primary school subjects were marginally higher.
The present study reports values and reference ranges of some haematological parameters for pre-primary and primary school aged children in Port Harcourt, Nigeria; no significant gender variations were observed in these parameters. The results indicate that significant differences exist in the values of some of the haematological parameters under investigation between pre-primary and primary school subjects. This suggests a distinction in the haematological parameters of both populations.
关于尼日利亚哈科特港学前和小学年龄段居民血液学参考值的已发表报告相对较少。
确定尼日利亚哈科特港学前和小学年龄段儿童某些血液学参数的参考范围。
随机招募了250名学前儿童，其中包括124名男性和126名女性，年龄在1至5岁之间；以及536名小学儿童，其中包括262名男性和274名女性，年龄在6至13岁之间，他们均居住在尼日利亚哈科特港。以最小淤滞量采集3 - 5毫升静脉血，并通过指定方法测定以下血液学参数的值：血细胞比容使用霍克斯利微量毛细管测定，以3000转/分钟离心10分钟。红细胞、白细胞（包括分类计数）和血小板细胞使用改良的纽鲍尔计数室进行手工计数。红细胞沉降率（ESR）使用魏氏法测定。血红蛋白浓度通过氰化高铁血红蛋白法测定。
给出了哈科特港学前和小学年龄段男、女儿童的血细胞比容、总白细胞、中性粒细胞和淋巴细胞分类计数、血小板细胞计数以及红细胞沉降率；血红蛋白浓度和红细胞计数的参考范围。在学前和小学儿童中，这些参数的值没有显著的性别差异。然而，与学前儿童相比，小学儿童（无论性别）的淋巴细胞分类计数和红细胞沉降率显著更高，血小板计数、总白细胞计数和中性粒细胞分类计数显著更低[p<0.05]。两个受试组之间的血细胞比容值没有显著差异；尽管小学儿童的值略高。
本研究报告了尼日利亚哈科特港学前和小学年龄段儿童某些血液学参数的值和参考范围；在这些参数中未观察到显著的性别差异。结果表明，在研究的一些血液学参数值方面，学前和小学儿童之间存在显著差异。这表明这两个人群的血液学参数存在差异。
