Okada H, Suzuki H, Murakami M, Ogata Y, Takenaka T, Sakaguchi H, Hosoda Y, Saruta T
Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan.
Jpn J Med. 1990 May-Jun;29(3):309-12. doi: 10.2169/internalmedicine1962.29.309.
An autopsy case of an elderly man with Takayasu's arteritis and atherosclerosis is presented. Ischemic signs and symptoms including anginal attack were aggravated with activity of arteritis despite administration of prednisolone throughout the entire course. The autopsy revealed severe atherosclerosis over the aorta and its branches, and arteritis in the fibrotic stage in localized area. Vessels of vital organs including heart and kidneys, did not show Takayasu's arteritis but were atherosclerotic. This case highlights the numerous problems encountered in the treatment of elderly patients with vasculitis such as Takayasu's arteritis.
本文报告一例患有高安动脉炎和动脉粥样硬化的老年男性尸检病例。尽管在整个病程中都使用了泼尼松龙，但包括心绞痛发作在内的缺血性症状随着动脉炎活动而加重。尸检显示主动脉及其分支存在严重动脉粥样硬化，局部区域处于纤维化阶段的动脉炎。包括心脏和肾脏在内的重要器官血管未显示高安动脉炎，但存在动脉粥样硬化。该病例凸显了老年血管炎患者（如高安动脉炎）治疗中遇到的诸多问题。
