Maghnie M, Valtorta A, Moretta A, Priora C, Preti P
Clinica Pediatrica, IRCCS Policlinico S. Matteo, Università di Pavia.
Medicina (Firenze). 1990 Apr-Jun;10(2):148-9.
Humoral and cellular immunologic parameters were evaluated in 13 prepuberal cryptorchid boys before, during and 3 months after hCG therapy. Before treatment, all the immunologic parameters were normal except for a higher percentage of T suppressor-cytotoxic cells (CD8+). During therapy, the percentage of CD8+ cells and lymphocyte response to ConA significantly decreased, and returned to the control level after hCG withdrawal. The possible effects of long-term hCG treatment on the immune system remains to be determined.
对13名青春期前隐睾男孩在人绒毛膜促性腺激素（hCG）治疗前、治疗期间及治疗后3个月的体液免疫和细胞免疫参数进行了评估。治疗前，除T抑制细胞毒性细胞（CD8+）百分比偏高外，所有免疫参数均正常。治疗期间，CD8+细胞百分比及淋巴细胞对刀豆蛋白A的反应显著降低，hCG停用后恢复至对照水平。长期hCG治疗对免疫系统的可能影响仍有待确定。
