钯敏感性的 10 年回顾性研究。
A 10-year retrospective study on palladium sensitivity.
机构信息
Department of Dermatology and Mayo Medical School, College of Medicine, Mayo Clinic, Rochester, MN 55905, USA.
出版信息
Dermatitis. 2009 Jul-Aug;20(4):208-13.
BACKGROUND
Palladium has become an important contact allergen because of increased use in industry, jewelry, and dentistry.
OBJECTIVE
To determine the frequency of palladium allergy in a US patch-test population tested to palladium.
METHODS
A 10-year retrospective review (1997-2006) was performed on patients sensitive to palladium at the Department of Dermatology, Mayo Clinic, Rochester, MN.
RESULTS
A total of 910 patients were tested to a series that included palladium chloride 2% in petrolatum. A palladium-positive patch-test result was noted in 110 patients (12.1%). Of the 106 patients sensitized to palladium who had records available for review, 15.1% had a diagnosis of lichen planus-like eruptions; 13.2%, burning mouth; 27.4%, stomatitis; and 29.2%, hand and body dermatitis.
CONCLUSION
Palladium sensitivity is more common in oral diseases than in skin. We describe a previously unknown high degree of co-reactivity of gold with palladium to the same degree as the known co-reactivity with nickel.
背景
由于钯在工业、珠宝和牙科领域的应用增加，钯已成为一种重要的接触过敏原。
目的
确定在接受钯斑贴试验的美国人群中钯过敏的频率。
方法
对明尼苏达州罗切斯特市梅奥诊所皮肤科对钯过敏的患者进行了一项为期 10 年的回顾性研究（1997-2006 年）。
结果
共有 910 例患者接受了包括 2%氯化钯的石油膏系列斑贴试验。110 例患者（12.1%）钯斑贴试验阳性。在可查阅记录的 106 例对钯敏感的患者中，15.1%的患者诊断为扁平苔藓样疹；13.2%的患者诊断为灼口综合征；27.4%的患者诊断为口炎；29.2%的患者诊断为手部和身体皮炎。
结论
钯过敏在口腔疾病中比在皮肤疾病中更为常见。我们描述了一种以前未知的高度同金与钯的共同反应性，其程度与已知的镍的共同反应性相同。
Zotero 插件