检测特应性和非特应性患者对牙科材料致敏的易感性。
Determination of susceptibility to sensitization to dental materials in atopic and non-atopic patients.
机构信息
Sergio Livingstone 943, Independencia. Santiago-Chile,
出版信息
Med Oral Patol Oral Cir Bucal. 2012 Mar 1;17(2):e320-4. doi: 10.4317/medoral.17424.
INTRODUCTION
Some studies report that atopic patients have a greater frequency of delayed-type sensitization than non-atopic patients.
OBJECTIVE
To determine the influence of the atopic condition on delayed sensitization to dental materials.
DESIGN
cross-sectional study.
METHODS
Forty (40) atopic subjects and forty (40) non-atopic subjects, of both sexes, between 20 and 65 years of age were included. The determination of delayed sensitization to dental materials was performed using patch test. An oral exam was also carried out to check for lesions of the oral mucosa.
RESULTS
61.25% of the patients were positive for delayed-type sensitization to one or more allergens, being palladium chloride (21.25%), ammoniated mercury (20%), benzoyl peroxide (12.5%) and amalgam (10%) the most frequent. The frequency of sensitization was 67.5% in the group of atopic patients, compared to 55% in the non atopic group (p>0.05). The materials with the greatest difference of sensitization in atopic compared to non-atopic patients were ammoniated mercury, benzoyl peroxide, amalgam and Bisphenol A Dimethacrylate (BIS-GMA).
CONCLUSION
The atopic condition is not related to a higher frequency of delayed sensitization to a battery of dental materials.
引言
一些研究报告称，特应性患者比非特应性患者更易发生迟发型过敏反应。
目的
确定特应性条件对牙科材料迟发性致敏的影响。
设计
横断面研究。
方法
纳入 40 名特应性受试者和 40 名非特应性受试者，均为 20 至 65 岁的男女。使用斑贴试验确定对牙科材料的迟发性致敏。还进行了口腔检查，以检查口腔黏膜的病变。
结果
61.25%的患者对一种或多种过敏原呈迟发型过敏反应，其中氯化钯（21.25%）、氨化汞（20%）、过氧化苯甲酰（12.5%）和汞合金（10%）最常见。特应性患者的致敏频率为 67.5%，而非特应性患者为 55%（p>0.05）。与非特应性患者相比，特应性患者对氨化汞、过氧化苯甲酰、汞合金和双酚 A 二甲基丙烯酸酯（BIS-GMA）等材料的致敏差异最大。
结论
特应性条件与对一系列牙科材料的迟发性过敏反应的频率增加无关。
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