Boyes D A, Pankratz E, Galliford B, White G M, Fairey R N, Yuen B H
Can Med Assoc J. 1977 Oct 8;117(7):753-6.
Over a period of 29 years 30 patients with gestational trophoblastic neoplasia were referred to the Cancer Control Agency of British Columbia. Five patients had benign disease and required no further treatment after having had dilatation and curettage. The remaining 25 patients were treated with methotrexate or hysterectomy, or both. Actuarial survival rates were 96.4% at 1 year and 90.6% at 5 years. There was a high correlation between malignancy and high titres of human chorionic gonadotropin (HCG). All cases of hydatidiform mole must be followed closely by means of estimations of HCG titre.
在29年的时间里，30例妊娠滋养细胞肿瘤患者被转诊至不列颠哥伦比亚癌症控制机构。5例患者患有良性疾病，在刮宫术后无需进一步治疗。其余25例患者接受了甲氨蝶呤或子宫切除术，或两者兼用。1年的精算生存率为96.4%，5年为90.6%。恶性肿瘤与高滴度人绒毛膜促性腺激素（HCG）之间存在高度相关性。所有葡萄胎病例都必须通过检测HCG滴度进行密切随访。
