转移性肾母细胞瘤放疗后发生的乳腺癌。
Breast carcinoma following radiotherapy of metastatic Wilm's tumor.
作者信息
Reimer R R, Fraumeni J F, Reddick R, Moorhead E L
出版信息
Cancer. 1977 Oct;40(4):1450-2. doi: 10.1002/1097-0142(197710)40:4<1450::aid-cncr2820400415>3.0.co;2-q.
Abstract
A 22-year-old women developed breast cancer 15 years after radiotherapy to the lung for metastatic Wilms tumor. Her 32-year-old mother died of bilateral breast cancer, suggesting a genetic predisposition to radiogenic cancer. Recent improvements in the survival of children with certain cancers necessitate long-term surveillance for iatrogenic neoplasia, particularly when familial susceptibility is evident.
摘要
一名22岁女性在因转移性肾母细胞瘤接受肺部放疗15年后患上乳腺癌。她32岁的母亲死于双侧乳腺癌，提示存在放射性癌症的遗传易感性。近期某些癌症患儿生存率的提高使得有必要对医源性肿瘤进行长期监测，尤其是在家族易感性明显的情况下。
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