2nd Department of Medicine and Cardiology Center, Medical Faculty, Albert Szent-Györgyi Clinical Center, University of Szeged, Szeged, Hungary.
Clin Exp Hypertens. 2009 Jun;31(4):380-7. doi: 10.1080/10641960903030186.
The aim of the present study was to assess the relationship between coronary flow velocity reserve (CFR), aortic distensibility indices, and levels of plasma total cholesterol (TC) in arterial hypertension. We studied 39 consecutive hypertensive patients free of coronary artery disease. Eighteen of them had normal TC and 21 had 1(8) high TC. Coronary flow velocity reserve and aortic elastic moduli were measured during stress transoesophageal echocardiography. Reduced CFR (2.41 + or - 0.75 vs. 1.97 + or - 0.60, p < 0.05), increased aortic elastic modulus (in 10(3) mmHg) (0.56 + or - 0.41 vs. 0.77 + or - 0.29, p < 0.05) and Young's modulus (in 10(3) mmHg) (5.42 + or - 4.03 vs. 8.57 + or - 4.79, p < 0.05) were found in hypercholesterolaemia.
本研究旨在评估冠状动脉血流储备（CFR）、主动脉顺应性指数与血浆总胆固醇（TC）水平在动脉高血压中的关系。我们研究了 39 例无冠心病的连续高血压患者。其中 18 例 TC 正常，21 例 TC 升高。在应激经食管超声心动图检查期间测量了冠状动脉血流储备和主动脉弹性模量。在高胆固醇血症中发现 CFR 降低（2.41 ± 0.75 比 1.97 ± 0.60，p < 0.05）、主动脉弹性模量增加（以 10（3）mmHg 计）（0.56 ± 0.41 比 0.77 ± 0.29，p < 0.05）和杨氏模量（以 10（3）mmHg 计）（5.42 ± 4.03 比 8.57 ± 4.79，p < 0.05）。
