Suppr超能文献

中老年男性和女性的低能量远端桡骨骨折——骨质疏松症和骨折风险的负担:一项对 1794 例连续患者的研究。

Low-energy distal radius fractures in middle-aged and elderly men and women--the burden of osteoporosis and fracture risk : A study of 1794 consecutive patients.

机构信息

Department of Surgical Sciences, Faculty of Medicine and Dentistry, University of Bergen, 5021, Bergen, Norway.

出版信息

Osteoporos Int. 2010 Jul;21(7):1257-67. doi: 10.1007/s00198-009-1068-x. Epub 2009 Oct 8.

Abstract

UNLABELLED

One third of 218 men and half of 1,576 women with low-energy distal radius fractures met the bone mineral density (BMD) criteria for osteoporosis treatment. A large proportion of patients with increased fracture risk did not have osteoporosis. Thus, all distal radius fracture patients >or=50 years should be referred to bone densitometry.

INTRODUCTION

Main objectives were to determine the prevalence of patients with a low-energy distal radius fracture in need of osteoporosis treatment according to existing guidelines using T-score <or= -2.0 or <or=-2.5 standard deviation (SD) and calculate their fracture risk.

METHODS

A total of 218 men and 1,576 women >or=50 years were included. BMD was assessed by dual energy X-ray absorptiometry (DXA) at femoral neck, total hip, and lumbar spine (L2-L4). The WHO fracture risk assessment tool (FRAX(R)) was applied to calculate the 10-year fracture risk.

RESULTS

T-scores <or=-2.0 and <or=-2.5 SD at femoral neck was found in 37.7% and 19.6% of men and 51.1% and 31.2% of women, respectively. The risk of hip fracture was 6.2% for men and 9.0% for women. The corresponding figures for patients with T-score <or=-2.0 SD were 11.6% and 14.5% and for T-score <or=-2.5 SD 16.3% and 18.2%, respectively. A large proportion of distal radius fracture patients with a high 10-year FRAX risk did not have osteoporosis.

CONCLUSIONS

Every second to every third fracture patient met the present BMD criteria for osteoporosis treatment. Because a large proportion of distal radius fracture patients did not have osteoporosis, treatment decisions should not be based on fracture risk assessment without bone densitometry. Thus, all distal radius fracture patients >or=50 years should be referred to bone densitometry, and if indicated, offered medical treatment.

摘要

目的

根据现有指南,使用 T 评分<-2.0 或<-2.5 个标准差(SD)确定需要骨质疏松治疗的低能量桡骨远端骨折患者的比例,并计算其骨折风险。

方法

共纳入 218 名男性和 1576 名>=50 岁的女性。通过双能 X 射线吸收法(DXA)评估股骨颈、全髋和腰椎(L2-L4)的骨密度。应用世界卫生组织(WHO)骨折风险评估工具(FRAX)计算 10 年骨折风险。

结果

男性和女性股骨颈 T 评分<-2.0 和<-2.5 SD 分别为 37.7%和 19.6%,51.1%和 31.2%。男性髋部骨折风险为 6.2%,女性为 9.0%。T 评分<-2.0 SD 的患者相应比例为 11.6%和 14.5%,T 评分<-2.5 SD 的患者为 16.3%和 18.2%。很大一部分桡骨远端骨折患者高 10 年 FRAX 风险但没有骨质疏松症。

结论

每两个到每三个桡骨远端骨折患者符合目前骨质疏松症治疗的 BMD 标准。由于很大一部分桡骨远端骨折患者没有骨质疏松症,因此不应根据骨折风险评估而不进行骨密度检测来做出治疗决策。因此,所有>=50 岁的桡骨远端骨折患者都应进行骨密度检测,如果有必要,应提供药物治疗。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验