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中老年男性和女性的低能量远端桡骨骨折——骨质疏松症和骨折风险的负担:一项对 1794 例连续患者的研究。

Low-energy distal radius fractures in middle-aged and elderly men and women--the burden of osteoporosis and fracture risk : A study of 1794 consecutive patients.

机构信息

Department of Surgical Sciences, Faculty of Medicine and Dentistry, University of Bergen, 5021, Bergen, Norway.

出版信息

Osteoporos Int. 2010 Jul;21(7):1257-67. doi: 10.1007/s00198-009-1068-x. Epub 2009 Oct 8.

DOI:10.1007/s00198-009-1068-x
PMID:19813045
Abstract

UNLABELLED

One third of 218 men and half of 1,576 women with low-energy distal radius fractures met the bone mineral density (BMD) criteria for osteoporosis treatment. A large proportion of patients with increased fracture risk did not have osteoporosis. Thus, all distal radius fracture patients >or=50 years should be referred to bone densitometry.

INTRODUCTION

Main objectives were to determine the prevalence of patients with a low-energy distal radius fracture in need of osteoporosis treatment according to existing guidelines using T-score <or= -2.0 or <or=-2.5 standard deviation (SD) and calculate their fracture risk.

METHODS

A total of 218 men and 1,576 women >or=50 years were included. BMD was assessed by dual energy X-ray absorptiometry (DXA) at femoral neck, total hip, and lumbar spine (L2-L4). The WHO fracture risk assessment tool (FRAX(R)) was applied to calculate the 10-year fracture risk.

RESULTS

T-scores <or=-2.0 and <or=-2.5 SD at femoral neck was found in 37.7% and 19.6% of men and 51.1% and 31.2% of women, respectively. The risk of hip fracture was 6.2% for men and 9.0% for women. The corresponding figures for patients with T-score <or=-2.0 SD were 11.6% and 14.5% and for T-score <or=-2.5 SD 16.3% and 18.2%, respectively. A large proportion of distal radius fracture patients with a high 10-year FRAX risk did not have osteoporosis.

CONCLUSIONS

Every second to every third fracture patient met the present BMD criteria for osteoporosis treatment. Because a large proportion of distal radius fracture patients did not have osteoporosis, treatment decisions should not be based on fracture risk assessment without bone densitometry. Thus, all distal radius fracture patients >or=50 years should be referred to bone densitometry, and if indicated, offered medical treatment.

摘要

目的

根据现有指南,使用 T 评分<-2.0 或<-2.5 个标准差(SD)确定需要骨质疏松治疗的低能量桡骨远端骨折患者的比例,并计算其骨折风险。

方法

共纳入 218 名男性和 1576 名>=50 岁的女性。通过双能 X 射线吸收法(DXA)评估股骨颈、全髋和腰椎(L2-L4)的骨密度。应用世界卫生组织(WHO)骨折风险评估工具(FRAX)计算 10 年骨折风险。

结果

男性和女性股骨颈 T 评分<-2.0 和<-2.5 SD 分别为 37.7%和 19.6%,51.1%和 31.2%。男性髋部骨折风险为 6.2%,女性为 9.0%。T 评分<-2.0 SD 的患者相应比例为 11.6%和 14.5%,T 评分<-2.5 SD 的患者为 16.3%和 18.2%。很大一部分桡骨远端骨折患者高 10 年 FRAX 风险但没有骨质疏松症。

结论

每两个到每三个桡骨远端骨折患者符合目前骨质疏松症治疗的 BMD 标准。由于很大一部分桡骨远端骨折患者没有骨质疏松症,因此不应根据骨折风险评估而不进行骨密度检测来做出治疗决策。因此,所有>=50 岁的桡骨远端骨折患者都应进行骨密度检测,如果有必要,应提供药物治疗。

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1
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2
Case finding for the management of osteoporosis with FRAX--assessment and intervention thresholds for the UK.采用FRAX工具进行骨质疏松症管理的病例发现——英国的评估与干预阈值
Osteoporos Int. 2008 Oct;19(10):1395-408. doi: 10.1007/s00198-008-0712-1. Epub 2008 Aug 28.
3
Special report on the 2007 adult and pediatric Position Development Conferences of the International Society for Clinical Densitometry.
Research trends and hotspots of Colles fracture: a bibliometric analysis from 1980 to 2023.
科雷氏骨折的研究趋势与热点:1980年至2023年的文献计量分析
Front Surg. 2025 Feb 19;12:1509556. doi: 10.3389/fsurg.2025.1509556. eCollection 2025.
4
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Medicina (Kaunas). 2025 Jan 27;61(2):227. doi: 10.3390/medicina61020227.
5
Trends and projection of forearm fractures including elbow fractures of the Olecranon in Sweden: an analysis of 363 968 fractures using public aggregated data.瑞典前臂骨折(包括鹰嘴骨折)的趋势和预测:使用公共汇总数据对 363968 例骨折的分析。
BMC Musculoskelet Disord. 2024 Jan 5;25(1):33. doi: 10.1186/s12891-023-07162-7.
6
Epidemiology of forearm fractures in women and men in Norway 2008-2019.挪威 2008-2019 年男女前臂骨折的流行病学研究。
Osteoporos Int. 2024 Apr;35(4):625-633. doi: 10.1007/s00198-023-06990-6. Epub 2023 Dec 12.
7
Epidemiology of distal radius fractures in Germany - incidence rates and trends based on inpatient and outpatient data.德国桡骨远端骨折的流行病学研究 - 基于住院和门诊数据的发病率和趋势。
Osteoporos Int. 2024 Feb;35(2):317-326. doi: 10.1007/s00198-023-06904-6. Epub 2023 Oct 11.
8
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9
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10
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国际临床骨密度测量学会2007年成人及儿科立场发展会议特别报告
Osteoporos Int. 2008 Oct;19(10):1369-78. doi: 10.1007/s00198-008-0689-9. Epub 2008 Jul 17.
4
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Osteoporos Int. 2008 Apr;19(4):385-97. doi: 10.1007/s00198-007-0543-5. Epub 2008 Feb 22.
5
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Osteoporos Int. 2008 Apr;19(4):437-47. doi: 10.1007/s00198-007-0550-6. Epub 2008 Feb 22.
6
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7
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8
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9
Characteristics of males over 50 years who present with a fracture: epidemiology and underlying risk factors.50岁以上男性骨折患者的特征:流行病学及潜在危险因素
J Bone Joint Surg Br. 2008 Jan;90(1):72-7. doi: 10.1302/0301-620X.90B1.18773.
10
Epidemiology of distal forearm fractures in Oslo, Norway.挪威奥斯陆前臂远端骨折的流行病学情况。
Osteoporos Int. 2008 Jun;19(6):781-6. doi: 10.1007/s00198-007-0499-5.