鉴定去唾液酸GM1作为大肠杆菌定植因子抗原的结合结构。
Identification of asialo GM1 as a binding structure for Escherichia coli colonization factor antigens.
作者信息
Orø H S, Kolstø A B, Wennerås C, Svennerholm A M
机构信息
Biotechnology Centre, Oslo, Norway.
出版信息
FEMS Microbiol Lett. 1990 Nov;60(3):289-92. doi: 10.1016/0378-1097(90)90319-l.
PMID:1982102
Abstract
We have examined the binding of colonization factor antigens, (CFAs) of enterotoxigenic Escherichia coli to gangliosides and asialo gangliosides by using immuno-thin layer chromatography. CFA/II and its subcomponents (CS1, CS2 and CS3) as well as the subcomponent CS4 of the CFA/IV complex bound to asialo ganglioside GM1.
摘要
我们利用免疫薄层层析法检测了产肠毒素大肠杆菌的定居因子抗原（CFAs）与神经节苷脂和去唾液酸神经节苷脂的结合情况。CFA/II及其亚组分（CS1、CS2和CS3）以及CFA/IV复合物的亚组分CS4与去唾液酸神经节苷脂GM1结合。
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