Suppr超能文献

体外冲击波碎石术(ESWL)与经皮肾镜取石术(PCNL)或逆行肾内手术(RIRS)治疗肾结石的比较

Extracorporeal shock wave lithotripsy (ESWL) versus percutaneous nephrolithotomy (PCNL) or retrograde intrarenal surgery (RIRS) for kidney stones.

作者信息

Srisubat Attasit, Potisat Somkiat, Lojanapiwat Bannakij, Setthawong Vasun, Laopaiboon Malinee

机构信息

Institute of Medical Research and Technology Assessment, Dept of Medical Services, Ministry of Public Health, Tiwanon, Nonthaburi, Thailand, 11000.

出版信息

Cochrane Database Syst Rev. 2009 Oct 7(4):CD007044. doi: 10.1002/14651858.CD007044.pub2.

Abstract

BACKGROUND

Stones in the urinary tract are a common medical problem in the general population. At present, the great expansion in minimally invasive techniques has led to the decrease in open surgery. Extracorporeal shock wave lithotripsy (ESWL) has been introduced as an alternative approach which disintegrates stones in the kidney and upper urinary tract through the use of shock waves. Nevertheless, as there are limitations with the success rate in ESWL, other minimally invasive modalities for kidney stones such as percutaneous nephrolithotomy (PCNL) and retrograde intrarenal surgery (RIRS) are also widely applied.

OBJECTIVES

To evaluate the effectiveness and complications of ESWL compared with PCNL or RIRS for managing kidney stones.

SEARCH STRATEGY

We searched the Cochrane Central Register of Controlled Trials (CENTRAL in The Cochrane Library), MEDLINE, EMBASE and reference lists of articles without language restriction.

SELECTION CRITERIA

Randomised controlled trials (RCTs) assessing the use of ESWL compared to PCNL or RIRS for kidney stone management.

DATA COLLECTION AND ANALYSIS

Two authors independently assessed all the studies for inclusion. Statistical analyses were performed using the random effects model and the results expressed as risk ratio (RR) for dichotomous outcomes or mean difference (MD) for continuous data with 95% confidence intervals (CI).

MAIN RESULTS

Three studies (214 patients) were included, however results could not be pooled. Two RCTs compared ESWL to PCNL. The success rate at three months for lower pole kidney stones was statistically higher for PCNL (RR 0.39, 95% CI 0.27 to 0.56). Re-treatment (RR 1.81, 95% CI 0.66 to 4.99) and using auxiliary procedures (RR 9.06, 95% CI 1.20 to 68.64) after PCNL were less compared to ESWL. The efficiency quotient (EQ) in PCNL was higher than ESWL. Hospital stay (MD -3.30 days, 95% CI -5.45 to -1.15), duration of treatment (MD -36.00 minutes, 95% CI -54.10 to -17.90) and complications were less for ESWL. One RCT compared ESWL versus RIRS for lower pole kidney stones. The success rate was not significantly different at the end of the third month (RR 0.91, 95% CI 0.64 to 1.30).

AUTHORS' CONCLUSIONS: Results from three small studies, with low methodological quality, indicated ESWL is less effective for lower pole kidney stones than PCNL but not significantly different from RIRS. Hospital stay and duration of treatment was less with ESWL. More RCTs are required to investigate the effectiveness and complications of ESWL for kidney stones compared to PCNL or RIRS.

摘要

背景

尿路结石是普通人群中常见的医学问题。目前,微创技术的巨大发展导致开放手术减少。体外冲击波碎石术(ESWL)已作为一种替代方法被引入,它通过使用冲击波使肾脏和上尿路的结石破碎。然而,由于ESWL成功率存在局限性,其他用于肾结石的微创方式,如经皮肾镜取石术(PCNL)和逆行肾内手术(RIRS)也被广泛应用。

目的

评估与PCNL或RIRS相比,ESWL治疗肾结石的有效性和并发症。

检索策略

我们检索了Cochrane对照试验中央注册库(Cochrane图书馆中的CENTRAL)、MEDLINE、EMBASE以及无语言限制的文章参考文献列表。

选择标准

评估ESWL与PCNL或RIRS用于肾结石治疗的随机对照试验(RCT)。

数据收集与分析

两位作者独立评估所有纳入研究。使用随机效应模型进行统计分析,结果以二分类结局的风险比(RR)或连续数据的平均差(MD)及95%置信区间(CI)表示。

主要结果

纳入三项研究(214例患者),但结果无法合并。两项RCT将ESWL与PCNL进行比较。PCNL治疗下极肾结石三个月时的成功率在统计学上更高(RR 0.39,95%CI 0.27至0.56)。与ESWL相比,PCNL后再次治疗(RR 1.81,95%CI 0.66至4.99)及使用辅助程序(RR 9.06,95%CI 1.20至68.64)的情况较少。PCNL的效率商(EQ)高于ESWL。ESWL的住院时间(MD -3.30天,95%CI -5.45至-1.15)、治疗持续时间(MD -36.00分钟,95%CI -54.10至-17.90)和并发症较少。一项RCT将ESWL与RIRS用于下极肾结石的情况进行比较。第三个月末的成功率无显著差异(RR 0.91,95%CI 0.64至1.30)。

作者结论

三项方法学质量较低的小型研究结果表明,ESWL治疗下极肾结石的效果不如PCNL,但与RIRS无显著差异。ESWL的住院时间和治疗持续时间较短。需要更多RCT来研究与PCNL或RIRS相比,ESWL治疗肾结石的有效性和并发症。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验