Quackenbush Katherine Elizabeth, Luna-Fineman Sandra, Magee James Fergall, Gundogan Munire, Golobi Mahin, Irie Takeshi, Fernandez Conrad Vincent
Dalhousie University, Halifax, Nova Scotia, Canada.
Pediatr Blood Cancer. 2009 Dec 15;53(7):1337-9. doi: 10.1002/pbc.22192.
Involvement of the falx cerebri in infants with stage 4 neuroblastoma is thought to be rare. The falx is derived from the neural crest and thus may be a location for primary neuroblastoma. Its propensity for metastasis is unknown. Management of neuroblastoma in this location is potentially challenging. We describe two children less than 18 months of age who were successfully managed with chemotherapy alone (without radiation or surgery) for falx involvement with neuroblastoma.
人们认为,大脑镰受累在4期神经母细胞瘤患儿中较为罕见。大脑镰起源于神经嵴,因此可能是原发性神经母细胞瘤的一个发病部位。其转移倾向尚不清楚。该部位神经母细胞瘤的治疗可能具有挑战性。我们描述了两名18个月以下的儿童,他们因神经母细胞瘤累及大脑镰,仅通过化疗(未进行放疗或手术)就成功治愈。