Department of Medicine, Georgetown University, Washington, D.C 20007, USA.
AIDS Patient Care STDS. 2009 Nov;23(11):965-71. doi: 10.1089/apc.2009.0134.
To determine prevalence and predictors of complementary and alternative medicine (CAM) use disclosure to health care providers and whether CAM use disclosure is associated with highly active antiretroviral therapy (HAART) adherence among HIV-infected women, we analyzed longitudinal data collected between October 1994 and March 2002 from HIV-infected CAM-using women enrolled in the Women's Interagency HIV Study. Repeated measures Poisson regression models were constructed to evaluate associations of selected predictors with CAM use disclosure and association between CAM use disclosure and HAART adherence. A total of 1,377 HIV-infected women reported CAM use during study follow-up and contributed a total of 4,689 CAM-using person visits. The overall prevalence of CAM use disclosure to health care providers was 36% across study visits. Women over 45 years old, with a college education, or with health insurance coverage were more likely to disclose their CAM use to health care providers, whereas women identified as non-Hispanic Black or other ethnicities were less likely to communicate their CAM usage. More health care provider visits, more CAM domains used, and higher health care satisfaction scores had significant relationships with increased levels of CAM use disclosure. Restricting analysis to use of herbal or nonherbal medications only, similar results were obtained. Compared to other CAM domains, mind-body practice had the lowest prevalence of CAM use disclosure. Additionally, CAM use disclosure was significantly associated with higher HAART adherence. From this study, we showed that a high percentage of HIV-infected women did not discuss their CAM use with health care providers. Interventions targeted towards both physicians and patients may enhance communication of CAM use, avoid potential adverse events and drug interactions, and enhance HAART adherence.
为了确定补充和替代医学(CAM)的使用披露给医疗保健提供者的流行率和预测因素,以及 CAM 使用披露是否与感染 HIV 的女性的高效抗逆转录病毒治疗(HAART)依从性相关,我们分析了 1994 年 10 月至 2002 年 3 月间从参加妇女机构间艾滋病毒研究的感染 HIV 的 CAM 使用女性中收集的纵向数据。构建了重复测量泊松回归模型,以评估选定的预测因素与 CAM 使用披露的关联,以及 CAM 使用披露与 HAART 依从性之间的关联。共有 1377 名感染 HIV 的女性在研究随访期间报告了 CAM 使用,并在总共 4689 次 CAM 使用人员就诊中提供了数据。在所有研究访视中,CAM 使用披露给医疗保健提供者的总体流行率为 36%。年龄在 45 岁以上、具有大学学历或拥有医疗保险的女性更有可能向医疗保健提供者披露其 CAM 使用情况,而被认定为非西班牙裔黑人或其他族裔的女性则不太愿意透露其 CAM 使用情况。更多的医疗保健提供者就诊、更多的 CAM 治疗领域使用以及更高的医疗保健满意度评分与 CAM 使用披露率的增加有显著关系。将分析仅限于草药或非草药药物的使用,也得到了类似的结果。与其他 CAM 治疗领域相比,身心实践的 CAM 使用披露率最低。此外,CAM 使用披露与更高的 HAART 依从性显著相关。从这项研究中,我们发现,很大比例的感染 HIV 的女性没有与医疗保健提供者讨论她们的 CAM 使用情况。针对医生和患者的干预措施可以增强 CAM 使用的沟通,避免潜在的不良事件和药物相互作用,并提高 HAART 的依从性。