Office of Blood Research and Review, Center for Biologics Evaluation and Research, US Food and Drug Administration, Rockville, Maryland 20852, USA.
Transfusion. 2009 Dec;49(12):2759-71. doi: 10.1111/j.1537-2995.2009.02429.x. Epub 2009 Oct 10.
Infections of humans with intraerythrocytic parasites of the genus Babesia can be locally prevalent in diverse regions of the United States. Transfusion of blood and blood products collected from donors infected with Babesia may result in a serious illness that can be fatal. In September 2008, the Food and Drug Administration organized a public workshop to discuss the various aspects of transfusion-transmitted babesiosis in the United States including the possible strategies to identify and defer blood donors who may have been infected with Babesia. Discussions were also held on the biology, pathogenesis, and epidemiology of Babesia species. In this article, we summarize the scientific presentations and panel discussions that took place during the workshop.
在美国的不同地区,人类感染血孢子虫属内红细胞内寄生虫的情况时有发生。因输注来自感染巴贝虫的供体的血液和血液制品而导致的严重疾病可能是致命的。2008 年 9 月,美国食品药品监督管理局组织了一次公开研讨会,讨论了美国输血传播巴贝斯虫病的各个方面,包括可能的策略来确定和推迟可能感染巴贝虫的献血者。还讨论了巴贝斯虫属的生物学、发病机制和流行病学。在本文中,我们总结了研讨会期间的科学报告和小组讨论。